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494796-54-2

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494796-54-2 Usage

General Description

(S)-3-(4-chlorophenyl)-2-hydroxypropionic acid, also known as (S)-ibuprofen, is a nonsteroidal anti-inflammatory drug (NSAID) that is commonly used for pain relief, reducing inflammation, and lowering fevers. It works by inhibiting the production of certain chemicals in the body that cause pain and inflammation. (S)-ibuprofen is often used to treat conditions such as arthritis, menstrual cramps, and minor injuries. It is available over-the-counter in many countries and is generally considered safe when used as directed, although it can cause side effects such as stomach irritation and increased risk of cardiovascular events.

Check Digit Verification of cas no

The CAS Registry Mumber 494796-54-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,9,4,7,9 and 6 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 494796-54:
(8*4)+(7*9)+(6*4)+(5*7)+(4*9)+(3*6)+(2*5)+(1*4)=222
222 % 10 = 2
So 494796-54-2 is a valid CAS Registry Number.

494796-54-2Upstream product

494796-54-2Relevant articles and documents

Highly enantioselective stereo-inverting sec-alkylsulfatase activity of hyperthermophilic Archaea

Wallner, Sabine R.,Nestl, Bettina M.,Faber, Kurt

, p. 2652 - 2656 (2005)

rac-sec-Alkyl sulfate esters 1a-8a were resolved in low to excellent enantioselectivities with E-values up to > 200 using whole cells of aerobically-grown hyperthermophilic sulfur-metabolizers, such as Sulfolobus solfataricus DSM 1617, Sulfolobus shibatae DSM 5389 and, most notably, Sulfolobus acidocaldarius DSM 639. Significantly enhanced selectivities were obtained using cells grown on sucrose-enriched Brock-medium. The stereochemical course of this biohydrolysis was shown to proceed with strict inversion of configuration, thus the preferred (R)-enantiomers were converted into the corresponding (S)-sec-alcohols to furnish a homochiral product mixture. The Royal Society of Chemistry 2005.

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