494841-74-6

Basic information

• Product Name: 2-Oxazolidinone, 3-[(2E)-3-(2-chloro-3-pyridinyl)-1-oxo-2-propenyl]-4,5-diphenyl-, (4R,5S)-
• CAS NO: 494841-74-6
• Molecular Formula: C23H17ClN2O3
• Molecular Weight: 404.853
• Mol File: 494841-74-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Oxazolidinone, 3-[(2E)-3-(2-chloro-3-pyridinyl)-1-oxo-2-propenyl]-4,5-diphenyl-, (4R,5S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Oxazolidinone, 3-[(2E)-3-(2-chloro-3-pyridinyl)-1-oxo-2-propenyl]-4,5-diphenyl-, (4R,5S)-(494841-74-6)
• EPA Substance Registry System: 2-Oxazolidinone, 3-[(2E)-3-(2-chloro-3-pyridinyl)-1-oxo-2-propenyl]-4,5-diphenyl-, (4R,5S)-(494841-74-6)

Safety Data

• Hazardous Substances Data: 494841-74-6(Hazardous Substances Data)

Upstream product

• 148247-84-1 3-(2-chloro-3-pyridinyl)-(E)-2-propenoic acid ethyl ester 
• 118419-93-5 3-(2-chloro-3-pyridinyl)-(E)-2-propenoic acid 
• 86286-50-2 (4R,5S)-4,5-diphenyl-1,3-oxazolidin-2-one 

Relevant articles and documents

Asymmetric synthesis of a selective endothelin a receptor antagonist

An asymmetric synthesis of a selective endothelin A receptor antagonist 1b is described. Asymmetric conjugate addition of aryllithium derived from 18 to the chiral oxazoline 17 followed by hydrolysis afforded 15 in 96% ee via purification as (S)-(-)-1-phe