494850-27-0

Usage

Molecular Structure

A complex structure consisting of a pyrrole ring attached to a 1-ethanol group and a 2-methyl-5-[4-(methylthio)phenyl] functional group.

Aromatic and Aliphatic Characteristics

Possesses both aromatic and aliphatic characteristics.

Reactivity

The presence of the thioether group suggests potential reactivity and interaction with other sulfur-containing compounds.

Potential Uses

May have potential uses in pharmaceuticals, agrochemicals, and materials science.

Building Block in Organic Synthesis

Could be used as a building block in organic synthesis to create more complex molecules.

Upstream product

• 3446-89-7 4-(Methylthio)benzaldehyde 
• 141-43-5 ethanolamine 
• 189501-33-5 1-[4-(methylthio)phenyl]pentane-1,4-dione 
• 197905-69-4 2-[2-(4-methylsulfanylphenyl)-2-oxoethyl]-3-oxobutanic acid methyl ester 
• 42445-46-5 2-bromo-1-(4-methylsulfanyl-phenyl)-ethanone 

Downstream Products

• 494850-87-2 methanesulfonic acid 2-[2-methyl-5-(4-methylsulfanyl-phenyl)-pyrrol-1-yl]-ethyl ester 
• 1064453-40-2 (S)-2-ethoxy-3-(4-(2-(2-methyl-5-(4-(methylthio)phenyl)-1H-pyrrol-1-yl)ethoxy)phenyl)propanoic acid sodium salt 

Relevant academic research and scientific papers

AN IMPROVED PROCESS FOR THE PREPARATION OF PYRROLE DERIVATIVES

The present invention relates to an improved process for the preparation of pyrroles derivatives having hypolipidemic and hypocholesteremic activities. In particular, the invention relates to an improved process for the preparation of 2- ethoxy-3-(4-(2-(2-methyl-5-(4-(methylthio)phenyl)-1H-pyrrol-1-yl)ethoxy) phenyl)propanoate and its pharmaceutically acceptable salts, hydrates, solvates, polymorphs or intermediates thereof. The invention also relates to an improved process for the preparation of mesylate compound (A1).

A PROCESS FOR PREPARATION OF PYRROLES HAVING HYPOLIPIDEMIC HYPOCHOLESTEREMIC ACTIVITIES

The present invention provides pyrroles having hypolipidemic hypocholesteremic activities. The invention provides saroglitazar and its pharmaceutically acceptable salts, hydrates, solvates, polymorphs or intermediates thereof. The invention also provides a process for the preparation of saroglitazar. The invention further provides intermediates as well process for preparation thereof.

Novel heterocyclic compounds having hypolipidemic, hypocholesteremic activities process for their preparation and pharmaceutical compositions containing them and their use in medicine

Novel β-aryl-α-substituted propanoic acids having hypolipidemic and hypocholesteremic activities.