494852-86-7 Usage
Uses
Used in Chemical Production:
2,6-Benzothiazolediamine, N2-propyl-(9CI) is used as a raw material or intermediate in the production of various chemical products. Its presence in the manufacturing process contributes to the development of dyes, pigments, and other colorants that are essential in various industries.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, 2,6-Benzothiazolediamine, N2-propyl-(9CI) is utilized as a key component in the synthesis of certain medications. Its chemical properties make it a valuable intermediate in the creation of drugs that address a range of health concerns.
Used in Rubber Chemicals Production:
2,6-Benzothiazolediamine, N2-propyl-(9CI) is also employed in the production of rubber chemicals, where it plays a crucial role in enhancing the performance and properties of rubber materials. Its inclusion in the formulation of rubber chemicals can improve the durability, flexibility, and resistance to various environmental factors.
Safety Precautions:
Given its potential to cause skin and eye irritation, as well as its harmful effects if ingested, inhaled, or absorbed through the skin, it is essential to implement appropriate safety measures when handling and storing 2,6-Benzothiazolediamine, N2-propyl-(9CI). This includes the use of personal protective equipment, proper ventilation, and adherence to established safety protocols to minimize the risk of exposure and ensure the well-being of those working with this chemical compound.
Check Digit Verification of cas no
The CAS Registry Mumber 494852-86-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,9,4,8,5 and 2 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 494852-86:
(8*4)+(7*9)+(6*4)+(5*8)+(4*5)+(3*2)+(2*8)+(1*6)=207
207 % 10 = 7
So 494852-86-7 is a valid CAS Registry Number.
494852-86-7Relevant academic research and scientific papers
Delmas, Florence,Di Giorgio, Carole,Robin, Maxime,Azas, Nadine,Gasquet, Monique,Detang, Claire,Costa, Muriel,Timon-David, Pierre,Galy, Jean-Pierre
, p. 2588 - 2594 (2002)
6-Nitro- and 6-amino-benzothiazoles bearing different chains in position 2 and their corresponding anthranilic acid derivatives were investigated for their in vitro antiparasitic properties against parasites of the species Leishmania infantum and Trichomonas vaginalis compared to their toxicity towards human monocytes. Biological investigations established that the antiprotozoal properties depended greatly on the chemical structure of the position 2 substitution-bearing group. Compound C1, 2-[(2-chloro-benzothiazol-6-yl) amino] benzoic acid, demonstrated an interesting antiproliferative activity towards parasites of the species T. vaginalis, while compound C11, 2-([2-[(2-hydroxyethyl) amino]-benzothiazol-6-yl] amino) benzoic acid, exhibited a promising activity against parasites of the species L. infantum in their intracellular amastigote form. Additional experiments established that compound C11, which was poorly toxic against the promastigote and the extracellular amastigote forms of the parasite, could improve host-protective mechanisms against Leishmania by preventing parasite internalization by macrophages and stimulating NO production, by means of a mechanism synergistically enhanced by the presence of gamma interferon.
