494854-35-2

Upstream product

• 877272-94-1 ethyl (2E)-3-{4-[({1-[(tert-butoxycarbonyl)amino]cyclopentyl}carbonyl)amino]phenyl}acrylate 
• 5048-82-8 (E)-ethyl 3-(4-aminophenyl)acrylate 
• 17191-44-5 1-{[(benzyloxy)carbonyl]amino}cyclopentanecarboxylic acid 

Downstream Products

• 1055321-11-3 (E)-Ethyl 3-(4-(1-(6-cyclohexyl-5-(4-methoxyphenyl)-2,3-dihydro-[1,4]oxazino[2,3,4-hi]indole-9-carboxamido)cyclopentanecarboxamido)phenyl)acrylate 
• 1055320-87-0 (2E)-3-[4-[[[1-[[(6-cyclohexyl-2,3-dihydro-5-phenyl-1,4-oxazino[2,3,4-hi]indol-9-yl)carbonyl]amino]cyclopentyl]carbonyl]amino]phenyl]-2-propenoic acid, ethyl ester 
• 1349019-80-2 ethyl (2E)-3-[4-[1-[[(13-cyclohexyl-6,7-dihydro-5H-indolo[2,1-a][2]benzazepin-10-yl)carbonyl]amino]cyclopentyl]phenyl]-propenoate 
• 928341-65-5 ethyl (2E)-3-(4-{[(1-{[(14-cyclohexyl-3-methoxy-6-methyl-5,6,7,8-tetrahydroindolo[2,1-a][2,5]benzodiazocine-11-yl)carbonyl]amino}cyclopentyl)carbonyl]amino}phenyl)acrylate 

Relevant academic research and scientific papers

TETRACYCLIC INDOLE DERIVATIVES AS ANTIVIRAL AGENTS

The present invention relates to tetracyclic indole derivatives of formula (I): wherein Ar, A, R1, R2, L, W, X, Y and Z are defined herein, and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising them, a

Inhibitors of HCV replication

Indole compounds of Formula I are described. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV. Different forms and compositions comprising the compounds are also described as well as methods of preparing the compounds.

INDOLE DERIVATIVES AS ANTIVIRAL AGENTS

The present invention relates to indole compounds of the formula (I): wherein R1, R2, R3, R4, A, E and X are as defined herein, and pharmaceutically acceptable salts thereof, useful in the prevention and treatment of hepatitis C infections.