494854-35-2

Upstream product

• 5048-82-8 (E)-ethyl 3-(4-aminophenyl)acrylate 
• 17191-44-5 1-{[(benzyloxy)carbonyl]amino}cyclopentanecarboxylic acid 
• 877272-94-1 ethyl (2E)-3-{4-[({1-[(tert-butoxycarbonyl)amino]cyclopentyl}carbonyl)amino]phenyl}acrylate 

Downstream Products

• 928341-65-5 ethyl (2E)-3-(4-{[(1-{[(14-cyclohexyl-3-methoxy-6-methyl-5,6,7,8-tetrahydroindolo[2,1-a][2,5]benzodiazocine-11-yl)carbonyl]amino}cyclopentyl)carbonyl]amino}phenyl)acrylate 
• 1055321-11-3 (E)-Ethyl 3-(4-(1-(6-cyclohexyl-5-(4-methoxyphenyl)-2,3-dihydro-[1,4]oxazino[2,3,4-hi]indole-9-carboxamido)cyclopentanecarboxamido)phenyl)acrylate 
• 1055320-87-0 (2E)-3-[4-[[[1-[[(6-cyclohexyl-2,3-dihydro-5-phenyl-1,4-oxazino[2,3,4-hi]indol-9-yl)carbonyl]amino]cyclopentyl]carbonyl]amino]phenyl]-2-propenoic acid, ethyl ester 
• 1349019-80-2 ethyl (2E)-3-[4-[1-[[(13-cyclohexyl-6,7-dihydro-5H-indolo[2,1-a][2]benzazepin-10-yl)carbonyl]amino]cyclopentyl]phenyl]-propenoate 

Relevant academic research and scientific papers

TETRACYCLIC INDOLE DERIVATIVES AS ANTIVIRAL AGENTS

The present invention relates to tetracyclic indole derivatives of formula (I): wherein Ar, A, R1, R2, L, W, X, Y and Z are defined herein, and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising them, a

INDOLE DERIVATIVES AS ANTIVIRAL AGENTS

The present invention relates to indole compounds of the formula (I): wherein R1, R2, R3, R4, A, E and X are as defined herein, and pharmaceutically acceptable salts thereof, useful in the prevention and treatment of hepatitis C infections.

Inhibitors of HCV replication

Indole compounds of Formula I are described. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV. Different forms and compositions comprising the compounds are also described as well as methods of preparing the compounds.