4951-05-7Relevant academic research and scientific papers
Cyclization of 4,5-diamino pyrazole derivatives and their antibacterial activities
Rizk, Hala F.,Ei-Badawi, Mahmoud A.,Ibrahim, Seham A.,Ei-Borai, Mohamed A.
, p. 1451 - 1459 (2011/10/30)
A convenient synthesis of intermediate 4,5-diamino-3-aryl-1-phenylpyrazoles 4a-4c was reported. The different cyclization reactions were carried out with chalcone, 2-mercaptoacetic acid and p-anisialdehyde, ethyl chloroformate, glyoxal and thiourea to afford different N and S containing heterocycles. The reaction conditions were compared by conventional heating and microwave irradiation. The structures of the cyclization products were determined by analytical and spectroscopic data. All the synthesized compounds were screened for antibacterial activities in vitro. Copyright
BISPYRAZOLEPYRAZINES AS SELF-CONDENSATION PRODUCTS FROM 4,5-DIAMINOPYRAZOLES
Orlov, V. D.,Kiroga, Kh.,Kolos, N. N.
, p. 1008 - 1011 (2007/10/02)
Bispyrazolopyrazines have been obtained by self-condensation of 4,5-diaminopyrazoles and their structure confirmed by independent synthesis.The spectral data for these compounds is discussed.
