495405-05-5Relevant academic research and scientific papers
Identification of phenylisoxazolines as novel and viable antibacterial agents active against gram-positive pathogens
Barbachyn, Michael R.,Cleek, Gary J.,Dolak, Lester A.,Garmon, Stuart A.,Morris, Joel,Seest, Eric P.,Thomas, Richard C.,Toops, Dana S.,Watt, William,Wishka, Donn G.,Ford, Charles W.,Zurenko, Gary E.,Hamel, Judith C.,Schaadt, Ronda D.,Stapert, Douglas,Yagi, Betty H.,Adams, Wade J.,Friis, Janice M.,Slatter, J. Gregory,Sams, James P.,Oien, Nancee L.,Zaya, Matthew J.,Wienkers, Larry C.,Wynalda, Michael A.
, p. 284 - 302 (2007/10/03)
A new and promising group of antibacterial agents, collectively known as the oxazolidinones and exemplified by linezolid (PNU-100766, marketed as Zyvox), have recently emerged as important new therapeutic agents for the treatment of infections caused by G
SUBSTITUTED AMINOPHENYL ISOXAZOLINE DERIVATIVES USEFUL AS ANTIMICROBIALS
-
, (2008/06/13)
The present invention provides novel substituted amionphenyl isoxazoline derivatives of formula I wherein R1 is H, alkyl, cycloalkyl, alkoxy, amino, or alkylamino; X and Y are the same and different and are H, F, or CH3; W is O, or S; Q is a 4-, 5-, 6-, 7-, or 9-membered heterocyclic moiety containing one or more nitrogen, sulfur and/or oxygen. The compounds of the invention are useful as antimicrobial agents for preventing and treating infectious diseases.
Substituted aminophenyl isoxazoline derivatives useful as antimicrobials
-
, (2008/06/13)
The present invention provides novel substituted amionphenyl isoxazoline derivatives of formula I STR1 wherein R1 is H, alkyl, cycloalkyl, alkoxy, amino, or alkylamino; X and Y are the same and different and are H, F, or CH3 ; W is O, or S; Q is a 4-, 5-, 6-, 7-, or 9-membered heterocyclic moiety containing one or more nitrogen, sulfur and/or oxygen. The compounds of the invention are useful as antimicrobial agents for preventing and treating infectious diseases.
