495417-28-2

Basic information

• Product Name: 4-Isoxazolecarboxylicacid,3-(3-chlorophenyl)-5-methyl-,ethylester(9CI)
• Synonyms: 4-Isoxazolecarboxylicacid,3-(3-chlorophenyl)-5-methyl-,ethylester(9CI);ethyl 3-(3-chlorophenyl)-5-methylisoxazole-4-carboxylate
• CAS NO: 495417-28-2
• Molecular Formula: C₁₃H₁₂ClNO₃
• Molecular Weight: 265.69
• Product Categories: ISOXAZOLE
• Mol File: 495417-28-2.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-Isoxazolecarboxylicacid,3-(3-chlorophenyl)-5-methyl-,ethylester(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Isoxazolecarboxylicacid,3-(3-chlorophenyl)-5-methyl-,ethylester(9CI)(495417-28-2)
• EPA Substance Registry System: 4-Isoxazolecarboxylicacid,3-(3-chlorophenyl)-5-methyl-,ethylester(9CI)(495417-28-2)

Safety Data

• Hazardous Substances Data: 495417-28-2(Hazardous Substances Data)

Upstream product

• 29203-59-6 3-chloro-N-hydroxybenzimidoyl chloride 
• 141-97-9 ethyl acetoacetate 
• 34158-71-9 3-chlorobenzaldehyde oxime 
• 587-04-2 m-Chlorobenzaldehyde 
• 54716-02-8 ethyl (E)-3-(1-pyrrolidino)-2-butenoate 

Downstream Products

• 1159600-29-9 {6-[3-(3-chloro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-pyridin-3-yl}-(1,1-dioxo-1λ⁶-thiomorpholin-4-yl)-methanone 
• 1159600-25-5 6-[3-(3-chloro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-nicotinic acid 
• 92545-95-4 3-(3-chloro-phenyl)-5-methyl-isoxazole-4-carboxylic acid 
• 1159600-23-3 6-[3-(3-chloro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-nicotinic acid methyl ester 
• 495417-32-8 [3-(3-chloro-phenyl)-5-methyl-isoxazol-4-yl]-methanol 

Relevant articles and documents

Synthesis and biological activity of ethyl 2-(5-methyl-3-arylisoxazole-4-carboxamido)-4-alkylthiazole-5-carboxylate

A series of novel ethyl 2-(5-methyl-3-arylisoxazole-4-carboxamido)-4-alkylthiazole-5-carboxylates I-1-6 were synthesized. The structures of all target compounds were characterized by 1H NMR, 13C NMR, IR,MS and elemental analyses. Their fungicidal and herbicidal activities were evaluated. The results of preliminary bioassays show that the title compounds I-4 possess 20-50% inhibition against most of the tested plants at the dosage of 150 g ai/ha, while the title compounds I-1-5 possess 32-58% inhibition against FusaHum graminearum, Thanatephorus cucumeris, Botrytis cinereapers and Fusarium oxysporum in vitro at the concentration of 100 mg/L.

PROCESS FOR THE PREPARATION OF ISOXAZOLYL-METHOXY-NICOTINIC ACIDS

The present invention relates to a process for the preparation of a compound of formula (I) which is useful as an intermediate in the preparation of active pharmaceutical compounds from a compound of formula (IV) wherein R1 and R2 ar

ISOXAZOLOPYRIDINE DERIVATIVES FOR USE IN THE TREATMENT OF HIF-MEDIATED CONDITIONS

The present invention relates to novel compounds of formula (I) capable of modulating the stability and/or activity of hypoxia inducible factor (HIF) by inhibiting the activity of at least one HIF hydroxylase enzyme.