49572-64-7 Usage
Uses
Used in Research and Chemical Synthesis:
3-Iodo-2-methyl-2H-indazole serves as a building block in the creation of various related compounds, contributing to the development of new molecules with potential applications in the biological and pharmaceutical sectors. Its unique structural features make it a valuable component in the synthesis of novel compounds.
Used in Medicinal Chemistry and Drug Discovery:
Due to its potential pharmacological and physiological effects, 3-iodo-2-methyl-2H-indazole is of interest to researchers studying the properties and activities of indazole derivatives. Its unique structural properties position it as a candidate for the development of drugs, particularly in areas where its specific characteristics can be leveraged to address unmet medical needs or improve existing therapeutic options.
Check Digit Verification of cas no
The CAS Registry Mumber 49572-64-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,9,5,7 and 2 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 49572-64:
(7*4)+(6*9)+(5*5)+(4*7)+(3*2)+(2*6)+(1*4)=157
157 % 10 = 7
So 49572-64-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H7IN2/c1-11-8(9)6-4-2-3-5-7(6)10-11/h2-5H,1H3
49572-64-7Relevant academic research and scientific papers
HISTONE DEMETHYLASE INHIBITORS
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Paragraph 0190; 0191; 0192; 0193, (2014/06/25)
The present invention relates generally to compositions and methods for treating cancer and neoplastic disease. Provided herein are substituted 3-aminopyridine derivative compounds, substituted 3-aminopyridazine derivative compounds, and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for inhibition histone demethylase. Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as prostate cancer, breast cancer, bladder cancer, lung cancer and/or melanoma and the like.
Convenient method for the 3-functionalization of isoindazoles
Bunnell, Aaron,O'Yang, Counde,Petrica, Andra,Soth, Michael J.
, p. 285 - 293 (2007/10/03)
The C-3 position of isoindazoles is readily functionalized by metalation with lithium diisopropylamide followed by reaction with a variety of electrophiles. Copyright Taylor & Francis LLC.
