49572-99-8Relevant articles and documents
TOLL-LIKE RECEPTOR 8 (TLR8)-SPECIFIC ANTAGONISTS AND METHODS OF MAKING AND USES THEREOF
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Page/Page column 52, (2019/05/22)
Toll-like receptor 8 (TLR8)-specific inhibitors and methods of using the same in individuals having an autoimmune disease or an inflammatory disorder.
Synthesis of phthalazinones via palladium(ii)-catalysed intramolecular oxidative C-H/C-H cross-coupling of N′-methylenebenzohydrazides
Matsuda, Takanori,Tomaru, Yuki,Matsuda, Yoshiya
supporting information, p. 2084 - 2087 (2013/04/23)
A palladium(ii)-catalysed intramolecular oxidative C-H/C-H cross-coupling of N′-methylenebenzohydrazides to phthalazin-1(2H)-ones has been developed. This cyclization is believed to mechanistically proceed via electrophilic ortho-palladation and subsequen
ALKYLATION OF 1-0X0-2-PHENYL(METHYL)-4-ARYL(METHYL)-1,2-DIHYDROPHTHALAZINES WITH TRIETHYLOXONIUM FLUOROBORATE
Volynets, N. F.,Samartseva, I. V.,Khramova, I. V.,Pavlova, L. A.
, p. 1342 - 1346 (2007/10/02)
1-Oxo-2-phenyl-4-aryl-1,2-dihydrophthalazines are alkylated by triethyloxonium fluoroborate at the N3 nitrogen atom, forming corresponding 1-oxo-1,2-dihydrophthalazinium tetrafluoroborates.Under the same conditions 1-oxo-2-methyl-4-phenyl(methy