496018-68-9

Basic information

• Product Name: 2-{[4-(4-chlorophenyl)-3-cyano-6-(2-thienyl)-2-pyridinyl]sulfanyl}-N-isopropylacetamide
• Synonyms: 2-{[4-(4-chlorophenyl)-3-cyano-6-(2-thienyl)-2-pyridinyl]sulfanyl}-N-isopropylacetamide
• CAS NO: 496018-68-9
• Molecular Formula: C21H18ClN3OS2
• Molecular Weight: 427.97012
• Mol File: 496018-68-9.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-{[4-(4-chlorophenyl)-3-cyano-6-(2-thienyl)-2-pyridinyl]sulfanyl}-N-isopropylacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{[4-(4-chlorophenyl)-3-cyano-6-(2-thienyl)-2-pyridinyl]sulfanyl}-N-isopropylacetamide(496018-68-9)
• EPA Substance Registry System: 2-{[4-(4-chlorophenyl)-3-cyano-6-(2-thienyl)-2-pyridinyl]sulfanyl}-N-isopropylacetamide(496018-68-9)

Safety Data

• Hazardous Substances Data: 496018-68-9(Hazardous Substances Data)

Upstream product

• 6028-91-7 1-(4-chlorophenyl)-3-(thiophen-2-yl)prop-2-en-1-one 
• 7357-70-2 Cyanothioacetamide 
• 75726-96-4 2-bromo-N-isopropylacetamide 

Relevant articles and documents

ANTIBACTERIAL FAB I INHIBITORS

Disclosed herein are antibacterial compounds that inhibit fabl, a NADH-dependent enoyl [acyl carrier protein] reductase enzyme in the fatty acid biosynthesis pathway. The compounds are represented by structural formulas Ia and Ib: R1 and R2 are independently monocyclic aryl or heteroaryl groups, wherein the groups represented by R1 and R2 are optionally substituted with one or more acyclic substituents; R3 is -H or an optionally substituted C1-C8 aliphatic, C3-C8 cycloaliphatic, aryl, or heteroaryl group. X1 is a bond or a C1-C3 alkylene chain that is optionally substituted with a C1-C4 alkyl or an acidic group. X2 is an aryl, heteroaryl or C3-C8 cycloaliphatic ring, wherein the group represented by X2 is optionally substituted with triazole, tetrazole, and/or one or more acyclic substituents.