496020-82-7Relevant academic research and scientific papers
Citraconic acid and its anhydride-based hetero-Diels–Alder reactions in the synthesis of new thiopyrano[2,3-d][1,3]thiazole derivatives
Zelisko, Nataliya,Karpenko, Olexandr,Muzychenko, Volodymyr,Gzella, Andrzej,Lesyk, Roman
, p. 964 - 970 (2021)
Novel rel-(5R,5aR,11bS)-5-methyl-2,6-dioxo-3,5a,6,11b-tetrahydro-2H,5H-chromeno[4?,3?:4,5]thiopyrano[2,3-d][1,3]thiazole-5-carboxylic acids were synthesized in 63–72% yields via tandem acylation-hetero-Diels–Alder reaction of 5-(2-hydroxybenzylidene)-4-th
Tandem hetero-Diels-Alder-hemiacetal reaction in the synthesis of new chromeno[4′,3′:4,5]thiopyrano[2,3-d]thiazoles
Lozynskyi, Andrii,Matiychuk, Vasyl,Karpenko, Olexandr,Gzella, Andrzej K.,Lesyk, Roman
, p. 1 - 5 (2017/03/01)
Novel rel-(5aR,6R,11bS)-6-hydroxy-3,5a,6,11b-tetrahydro-2H,5H-chromeno[4′,3′:4,5]thiopyrano[2,3-d][1,3]thiazole-2-ones were synthesized via tandem hetero-Diels-Alder-hemiacetal reaction of 5-(2-hydroxybenzylidene)-4-thioxo-2-thiazolidinones and α,β-unsaturated aldehydes. The stereochemistry of cycloadditions was confirmed by NMR spectra and a single crystal X-ray diffraction analysis.
Arylidene Pyruvic Acids Motif in the Synthesis of New 2H,5H-Chromeno[4′,3′:4,5]thiopyrano[2,3-d]thiazoles via Tandem Hetero-Diels-Alder-Hemiacetal Reaction
Lozynskyi, Andrii,Zimenkovsky, Borys,Gzella, Andrzej K.,Lesyk, Roman
, p. 2266 - 2270 (2015/09/22)
We have developed a tandem hetero-Diels-Alder-hemiacetal reaction using arylidene pyruvic acids with 5-(ortho-hydroxybenzylidene)-substituted 4-thioxo-2-thiazolidinones, leading to 6-hydroxy-2-oxo-5-phenyl-3,5a,6,11b-tetrahydro-2H,5H-chromeno[4′,3′:4,5]thiopyrano[2,3-d][1,3]thiazole-6-carboxylic acids. The stereochemistry of cycloaddition was confirmed by NMR spectra and a single-crystal x-ray diffraction analysis.
Synthesis of fused thiopyrano[2,3-d][1,3]thiazoles via hetero-Diels-Alder reaction related tandem and domino processes
Zelisko, Nataliya,Atamanyuk, Dmytro,Ostapiuk, Yuri,Bryhas, Andriy,Matiychuk, Vasyl,Gzella, Andrzej,Lesyk, Roman
, p. 9501 - 9508 (2015/11/18)
Various novel rel-(5R,5aR,11bS)-2,6-dioxo-3,5a,6,11b-tetrahydro-2H,5H-chromeno[4′,3′:4,5]thiopyrano[2,3-d][1,3]thiazole-5-carboxylic acid derivatives were synthesized via hetero-Diels-Alder reaction related acylation-based tandem processes of 5-(ortho-hyd
Crotonic, cynnamic, and propiolic acids motifs in the synthesis of thiopyrano[2,3-d][1,3]thiazoles via hetero-Diels-Alder reaction and related tandem processes
Zelisko, Nataliya,Atamanyuk, Dmytro,Vasylenko, Olexandr,Bryhas, Andriy,Matiychuk, Vasyl,Gzella, Andrzej,Lesyk, Roman
, p. 720 - 729 (2014/02/14)
Various novel thiopyrano[2,3-d][1,3]thiazol-2-one-6-carboxylic acids derivatives were synthesized in 54-86% yields via hetero-Diels-Alder reactions and related acylation-based tandem processes of 5-arylidene-4-thioxo-2- thiazolidinones with crotonic, prop
