496043-74-4Relevant academic research and scientific papers
Bis-styrylpyridine and bis-styrylbenzene derivatives as inhibitors for Aβ fibril formation
Byeon, Seong Rim,Lee, Ji Hoon,Sohn, Ji-Hoon,Kim, Dong Chan,Shin, Kye Jung,Yoo, Kyung Ho,Mook-Jung, Inhee,Lee, Won Koo,Kim, Dong Jin
, p. 1466 - 1470 (2007/10/03)
New bis-styrylpyridine and bis-styrylbenzene derivatives were designed and synthesized. These 34 compounds were evaluated by Aβ fibril formation inhibitory assay using thioflavin T as a dye (named ThT assay). Most of them showed excellent inhibitory activ
Synthesis and coordination properties of palladium(II) and platinum(II) complexes with phosphonated triphenylphosphine derivatives
Rohlík, Zbyněk,Holzhauser, Petr,Kotek, Jan,Rudovsky, Jakub,Němec, Ivan,Hermann, Petr,Luke?, Ivan
, p. 2409 - 2423 (2007/10/03)
Two triphenylphosphine derivatives, diethyl [4-(diphenylphosphanyl)benzyl]phosphonate (3a) and tetraethyl {[5-(diphenylphosphanyl)-1,3-phenylene]dimethylene}bis(phosphonate) (3b), and also the corresponding free acids 4a and 4b were prepared. These ligands were characterized by 1H, 13C and 31P NMR spectroscopy and mass spectrometry. A full set of their Pd(II) and Pt(II) complexes of the general formula [MCl2L2] and one dinuclear complex trans-[Pd2Cl4(3a)2] were synthesized and their isomerization behaviour in solution was studied. The complexes were characterized by 1H, 13C, 31P and 195Pt NMR spectroscopy, mass spectrometry and far-IR spectroscopy. The X-ray structures of all complexes with 3a or 3b have usual slightly distorted square-planar geometry on the metal ion. Salts of phosphonic acids 4a and 4b and their complexes are freely soluble in aqueous solution; therefore, they can be potentially useful in aqueous or biphasic catalysis.
Synthesis of novel cross-conjugated dendritic fluorophores containing both phenylenevinylene and phenyleneethynylene moieties
Diez-Barra, Enrique,Garcia-Martinez, Joaquin C.,Rodriguez-Lopez, Julian
, p. 832 - 838 (2007/10/03)
New dendrons and dendrimers with dendritic arms composed of alternate phenyleneethynylene and phenylenevinylene moieties have been efficiently synthesized using orthogonal and convergent syntheses that combine Sonogashira and Horner-Wadsworth-Emmons react
