496063-16-2Relevant academic research and scientific papers
Indanylacetic acids as PPAR-δ activator insulin sensitizers
Wickens, Philip,Zhang, Chengzhi,Ma, Xin,Zhao, Qian,Amatruda, John,Bullock, William,Burns, Michael,Cantin, Louis-David,Chuang, Chih-Yuan,Claus, Thomas,Dai, Miao,Dela Cruz, Fernando,Dickson, David,Ehrgott, Frederick J.,Fan, Dongping,Heald, Sarah,Hentemann, Martin,Iwuagwu, Christiana I.,Johnson, Jeffrey S.,Kumarasinghe, Ellalahewage,Ladner, David,Lavoie, Rico,Liang, Sidney,Livingston, James N.,Lowe, Derek,Magnuson, Steve,Mannelly, Gretchen,Mugge, Ingo,Ogutu, Herbert,Pleasic-Williams, Susan,Schoenleber, Robert W.,Shapiro, Jeff,Shelekhin, Tatiana,Sweet, Laurel,Town, Christopher,Tsutsumi, Manami
, p. 4369 - 4373 (2008/02/12)
A series of indane acetic acid derivatives were prepared which show a spectrum of activity as insulin sensitizers and PPAR-α and PPAR-δ ligands. In vivo data are presented for insulin sensitizers with selectivity for PPAR-δ over PPAR-α.
