49615-25-0Relevant articles and documents
Synthesis and antimicrobial activities of new polyhalogenated benzimidazoles
Laudy, Agnieszka E.,Moo-Puc, Rosa,Cedillo-Rivera, Roberto,Kazimierczuk, Zygmunt,Orzeszko, Andrzej
, p. 1059 - 1065 (2012)
A series of new polyhalogenated benzimidazoles has been synthesized and their antibacterial and antiprotozoal activity was evaluated. Several of new substituted halogenobenzimidazoles and their 2'-deoxynucleosides showed noteworthy antiprotozoal toxicity particularly against Giardia lamblia. The most potent agents against bacteria and fungi were 4,5,6,7-tetrachlorobenzimidazoles with polyfluoroalkyl chain at position 2 of the heterocyclus.