49619-88-7

Usage

Family

Chromenones

Composition

Functional Groups:
Methoxy
Carbonyl
Phenyl
Core Structure: Chromenone

Biological Activities

Antioxidant
Anti-inflammatory
Anticancer

Potential Applications

Drug candidate for various therapeutic purposes

Research Status

Ongoing research and development in pharmaceutical and biomedical fields.

Upstream product

• 2748-98-3 3-(4-formylphenoxy)-4-methoxybenzaldehyde 
• 621-59-0 isovanillin 
• 459-57-4 4-fluorobenzaldehyde 
• 33554-52-8 3′-hydroxy-5,7,4′-trimethoxyflavone 
• 90-24-4 2-hydroxy-4,6-dimethoxyacetophenone 
• 1122-91-4 4-bromo-benzaldehyde 
• 104-88-1 4-chlorobenzaldehyde 
• 76554-31-9 3-(4-chlorophenyl)-1-(2-hydroxy-4,6-dimethoxyphenyl)prop-2-en-1-one 
• 720676-01-7 2-hydroxy-4,6-dimethoxy-4'-fluorochalcone 
• 38186-71-9 2′,3-dihydroxy-4,4′,6′-trimethoxychalcone 

Downstream Products

• 50276-96-5 Ochnaflavone 

Relevant academic research and scientific papers

Synthesis of ochnaflavone and its inhibitory activity on PGE2 production

Ochnaflavone, a naturally occurring biflavonoid composed of two units of apigenin (5,7,4′-trihydroxyflavone) joined via a C-O-C linkage, was first synthesized and evaluated its inhibitory activity on PGE2 production. Total synthesis was accompl

Total synthesis of ochnaflavone

The first total syntheses of ochnaflavone, an asymmetric biflavone consisting of apigenin and luteolin moieties, and the permethyl ether of 2,3,2'',3''-tetrahydroochnaflavone have been achieved. The key steps in the synthesis of ochnaflavone were the formation of a diaryl ether and ring cyclization of an ether-linked dimeric chalcone to assemble the two flavone nuclei. Optimal experimental conditions for the oxidative cyclization to form ochnaflavone were established.