4963-01-3 Usage
Uses
Used in Pharmaceutical Industry:
ISOMITRAPHYLLINE is used as a pharmaceutical compound for its potential therapeutic properties. Its unique structure and functional groups may contribute to its biological activity and potential applications in drug development.
Used in Research and Development:
ISOMITRAPHYLLINE is used as a research compound for studying its chemical properties, structure, and potential interactions with biological systems. This can help in understanding its mechanism of action and exploring its potential uses in various applications.
Used in Traditional Medicine:
ISOMITRAPHYLLINE may be used in traditional medicine for its potential therapeutic effects. Its presence in the leaves of M. speciosa Korth suggests that it may have been used in traditional remedies for various ailments.
References
Beckett et al., J. Pharm. Pharmacol., 17,753 (1965)
Beckett et ai., Planta Med., 14, 266 (1966)
Structure:
Finch, Taylor., J. Amer. Chem. Soc., 84,3871 (1962)
Prepara tion:
Seaton et al., Can. J. Chem., 38, 1035 (1960)
Check Digit Verification of cas no
The CAS Registry Mumber 4963-01-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,9,6 and 3 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 4963-01:
(6*4)+(5*9)+(4*6)+(3*3)+(2*0)+(1*1)=103
103 % 10 = 3
So 4963-01-3 is a valid CAS Registry Number.
InChI:InChI=1/C21H24N2O4/c1-12-14-10-23-8-7-21(16-5-3-4-6-17(16)22-20(21)25)18(23)9-13(14)15(11-27-12)19(24)26-2/h3-6,11-14,18H,7-10H2,1-2H3,(H,22,25)/t12-,13-,14+,18-,21-/m0/s1
4963-01-3Relevant academic research and scientific papers
Analysis of the kinetics of isomerization of spiro oxindole alkaloids
Laus, Gerhard,Broessner, Dagmar,Senn, Gilbert,Wurst, Klaus
, p. 1931 - 1936 (2007/10/03)
The isomerization of the spiro oxindole alkaloids mitraphylline, isomitraphylline, pteropodine, isopteropodine, speciophylline and uncarine F in water has been studied at several temperatures and the rate coefficients have been determined. The effect of pH on the rate of reaction and the equilibrium composition has been investigated. The rate coefficients in water and in organic solvents correlate satisfactorily with the Dimroth-Reichardt solvent polarity parameter. The present results support the existence of a zwitterionic intermediate stabilized by polar solvents and show that protonation of the alkaloids inhibits the isomerization. The crystal structure of pteropodine has been determined.
