49640-44-0

Upstream product

• 107907-98-2 (2-Benzyloxycarbamoyl-1-hydroxy-2-methyl-propyl)-carbamic acid tert-butyl ester 
• 106334-44-5 (1-Benzyloxy-3,3-dimethyl-4-oxo-azetidin-2-yl)-carbamic acid tert-butyl ester 
• 107908-00-9 N-Benzyloxy-2,2-dimethyl-3-oxo-propionamide 
• 4835-90-9 3-Hydroxy-2,2-dimethylpropanoic acid 
• 622-33-3 N-benzyloxyamine 

Downstream Products

• 87058-43-3 4-Benzyloxyimino-5,5-dimethyl-1,3-dioxan-2-on 
• 69956-53-2 3-Benzyloxy-5,6-dihydro-5,5-dimethyl-2H-1,3-oxazin-2,4(3H)-dion 
• 71663-75-7 N-(benzyloxy)-3,3-dimethyl-2-azetidinone 
• 69956-51-0 3-Benzyloxy-1,5-bis-(3-chlorphenyl)-biuret 
• 69956-50-9 Propionamid 
• 51457-94-4 1-Benzyloxy-3-(m-chlorphenyl)-harnstoff 
• 69956-52-1 3-(3-chloro-phenyl)-5,5-dimethyl-[1,3]oxazinane-2,4-dione 

Relevant academic research and scientific papers

β-LACTAM SYNTHESIS: CYCLIZATION VERSUS 1,2-ACYL MIGRATION-CYCLIZATION. THE MECHANISM OF THE 1,2-ACYL MIGRATION-CYCLIZATION

The cyclization of hydroxamate 1 unexpectedly afforded two isomeric β-lactams 2 and 3.The mechanism for the formation of 3 has been shown by carbon-13 labeling to involve a novel 1,2-acyl migration-cyclization process.