49645-94-5Relevant academic research and scientific papers
Novel thymol bearing oxypropanolamine derivatives as potent some metabolic enzyme inhibitors – Their antidiabetic, anticholinergic and antibacterial potentials
Zengin, Mustafa,Genc, Hayriye,Taslimi, Parham,Kestane, Ali,Guclu, Ertugrul,Ogutlu, Aziz,Karabay, Oguz,Gul?in, ?lhami
, p. 119 - 126 (2018)
A series of classical and newly synthesized thymol bearing oxypropanolamine compounds were synthesized and characterized. Their in vitro antibacterial activity on A. baumannii, P. aeruginosa, E. coli and S. aureus strains were investigated with agar well
Regioselective cleavage of 2-aryloxymethyloxiranes to 3-aryloxy-l- halogenopropan-2-ols
Maciejewski,Poltorak,Kaminska
experimental part, p. 595 - 604 (2009/12/26)
A series of new 2-ary loxymethy loxiranes prepared from epichlorohydrin and substituted phenols was subjected to nucleophilic opening of the oxirane ring. A comparison of regioselectivity and product yield for oxirane cleavage by means of aqueous hydrohalogenic acids or lithium tetrahalogenocuprates under anhydrous conditions was performed. The latter method provided very high regioselectivity for 3-aryloxy-l-halo-genopropan-2-ols as well as excellent yields.
Synthesis, β-adrenergic blocking activity and β-receptor binding affinities of 1-substituted-3-(2-isopropyl-5-methyl-phenoxy)-propan-2-ol oxalates
Jindal, Dharam Paul,Coumar, Mohane S.,Nandakumar,Bodhankar, Subhash Laxmanrao,Purohit, Prasad Gopal,Mahadik, Kakasaheb Ramoo,Bruni, Giancarlo,Collavoli, Elga,Massarelli, Paola
, p. 557 - 562 (2007/10/03)
The compounds 1-isopropylamino-3-(2-isopropyl-5-methyl-phenoxy)-propan-2-ol oxalate (5) and 1-tert-butylamino-3-(2-isopropyl-5-methyl-phenoxy)-propan-2-ol oxalate (6) were synthesized from thymol (1), a naturally occurring agent in Thymus vulgaris L. Phar
Synthesis and &β-Adrenergic Blocking Activity of 1--4-arylpiperazines
Samant, S. D.,Gupte, S. M.,Kulkarni, R. A.
, p. 524 - 525 (2007/10/02)
Condensation of thymol (II) with epichlorohydrin gives the corresponding glycidyl ether (III) which on treatment with N-arylpiperazines furnishes 1--4-arylpiperazines (IVa-g).These compounds (IVa-g) have been found to exhibit hypotensive activity.
