4965-78-0

Basic information

• Product Name: (25R)-3β-O-(p-toluenesulfonyloxy)spirost-5-ene
• Synonyms: (25R)-3β-O-(p-toluenesulfonyloxy)spirost-5-ene
• CAS NO: 4965-78-0
• Molecular Weight: 568.818
• Mol File: 4965-78-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (25R)-3β-O-(p-toluenesulfonyloxy)spirost-5-ene(CAS DataBase Reference)
• NIST Chemistry Reference: (25R)-3β-O-(p-toluenesulfonyloxy)spirost-5-ene(4965-78-0)
• EPA Substance Registry System: (25R)-3β-O-(p-toluenesulfonyloxy)spirost-5-ene(4965-78-0)

Safety Data

• Hazardous Substances Data: 4965-78-0(Hazardous Substances Data)

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 512-04-9 diosgenin 
• 512-06-1 yamogenin 

Downstream Products

• 116292-24-1 (25R)-5-spirosten-3β-methyl ether 
• 20470-24-0 (25R)-3β-hydroxy-5α-spirostan-6-one 

Relevant articles and documents

Mimicking natural phytohormones. 26-Hydroxycholestan-22-one derivatives as plant growth promoters

26-Hydroxycholestan-22-one derivatives with oxygenated functions in the rings A and/or B were successfully synthesized from diosgenin. After the modifications of rings A and B, the spiroketal side chain was selectively opened through a Lewis acid mediated

Diosgenin-based thio(seleno)ureas and triazolyl glycoconjugates as hybrid drugs. Antioxidant and antiproliferative profile

Abstract The stereoselective preparation of diosgenin-derived thio(seleno)ureas and glycomimetics bearing a 1,2,3-triazolyl tether on C-3 has been accomplished. The key steps in the synthetic pathway are the incorporation of an amino moiety and its furthe

Synthesis and characterization of new chiral liquid crystal monomers containing steroid unit

To reduce the bulky steric hindrance, improve the reactivity of diosgenin and cholesterol, and obtain mesophase of their derivatives, the commercially available cholesterol and diosgenin were allowed to be structurally modified. Four new chiral LC intermediate compounds (c～f) and the corresponding monomers (M1?M4) with different longer spacer were synthesized. The chemical structures, optical texture, thermal behavior and mesophase structure of all the mesogenic compounds obtained in this study were characterized by FT-IR, 1H-NMR, polarizing optical microscopy, differential scanning calorimetry, and X-ray diffraction measurements. The experimental results showed that the intermediate compounds containing diosgenyl groups c and d only showed a mesophase and exhibited fan-shaped texture of a smectic A (SA) phase, while the compounds containing terminal cholesteryl groups e and f showed two mesophases and exhibited fan-shaped texture of a SA phase, and oily streak texture and focal conic texture of cholesteric phase, respectively. The four chiral monomers M1?M4 all revealed cholesteric oily streak texture and focal conic texture. In addition, the melting temperature (Tm) and isotropic temperature (Ti) of the mesogenic compounds decreased with increasing the flexible spacer length. Compared with the intermediate compounds or monomers based on cholesterol, the compounds or monomers based on diosgenin showed higher Tm and Ti.