4965-79-1Relevant academic research and scientific papers
Sarsasapogenin-structure-modified derivatives, pharmaceutical compositions thereof and applications of the compositions
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Paragraph 0119-0122, (2017/07/20)
The invention relates to sarsasapogenin-structure-modified derivatives. The derivatives are characterized in that the structure formulas of the derivatives are shown as (I) and (II); pharmaceutical compositions of the derivatives and applications thereof are also provided; and many of the newly synthesized compounds show activity superior to activity of lead compounds through activity testing aiming at AD related targets. The compositions have high practical value for treating senile dementia. Defects of sarsasapogenin-structure-modified derivatives in the prior art are made up. The derivatives and the compositions are of great significance.
