496808-04-9

Usage

Uses

Used in Pharmaceutical Industry:
1-(N-METHYLPIPERIDIN-4-YL-METHYL)PIPERAZINE is used as a key intermediate in the synthesis of various pharmaceutical drugs and research chemicals due to its ability to enhance the central nervous system's activity.
Used in Neurological Disorder Treatment:
In the field of neurology, 1-(N-METHYLPIPERIDIN-4-YL-METHYL)PIPERAZINE is used as a potential treatment for neurological disorders such as Parkinson's disease and depression, leveraging its stimulant effects on the central nervous system to ameliorate symptoms.
Used in Antipsychotic Medication Development:
1-(N-METHYLPIPERIDIN-4-YL-METHYL)PIPERAZINE is also utilized as a component in the development of antipsychotic medications, where its influence on the central nervous system may contribute to managing the symptoms of certain mental health conditions.

InChI:InChI=1/C11H23N3/c1-13-6-2-11(3-7-13)10-14-8-4-12-5-9-14/h11-12H,2-10H2,1H3

Upstream product

• 205059-44-5 (1-methyl-4-piperidinyl)-1-piperazinylmethanone 

Downstream Products

• 866562-76-7 2-[4-(1-methyl-piperidin-4-ylmethyl)-piperazin-1-yl]-N,N-diphenyl-acetamide 
• 878161-24-1 4-(1-Methyl-piperidin-4-ylmethyl)-piperazin-1-carboxylic acid benzhydryl-amide 
• 549510-92-1 4-(1-Methyl-piperidin-4-ylmethyl)-piperazine-1-carboxylic acid 4-(5-trifluoromethyl-pyridin-2-yloxy)-phenyl ester 
• 727360-63-6 1-[4-(1-methyl-piperidin-4-ylmethyl)piperazin-1-yl]-3,3-diphenyl-propan-1-one 
• 1024588-12-2 N'-(5-bromo-2-cyano-4-pyrimidinyl)-N'-cyclohexyl-3-({4-[(1-methyl-4-piperidinyl)methyl]-1-piperazinyl}methyl)benzohydrazide trifluoroacetate 
• 1024588-16-6 N'-(5-bromo-2-cyano-4-pyrimidinyl)-4-({4-[(1-methyl-4-piperidinyl)methyl]-1-piperazinyl}methyl)-N'-(tetrahydro-2H-pyran-4-yl)benzohydrazide trifluoroacetate 
• 1024588-26-8 N'-(5-chloro-2-cyano-4-pyrimidinyl)-4-({4-[(1-methyl-4-piperidinyl)methyl]-1-piperazinyl}methyl)-N'-(tetrahydro-2H-pyran-4-yl)benzohydrazide trifluoroacetate 
• 1024587-70-9 N'-(5-bromo-2-cyano-4-pyrimidinyl)-N'-cyclopentyl-4-({4-[(1-methyl-4-piperidinyl)methyl]-1-piperazinyl}methyl)benzohydrazide trifluoroacetate 
• 1024587-86-7 N'-(5-bromo-2-cyano-4-pyrimidinyl)-N'-cyclopentyl-3-({4-[(1-methyl-4-piperidinyl)methyl]-1-piperazinyl}methyl)benzohydrazide trifluoroacetate 
• 1024587-94-7 N'-(5-bromo-2-cyano-4-pyrimidinyl)-N'-cyclohexyl-4-({4-[(1-methyl-4-piperidinyl)methyl]-1-piperazinyl}methyl)benzohydrazide trifluoroacetate 
• 1018822-17-7 (S)-2-((2-(4-methoxy-2,6-dimethylphenylsulfonyl)-1,2,3,4-tetrahydroisoquinolin-3-yl)-methoxy)-1-(4-((1-methylpiperidin-4-yl)methyl)piperazin-1-yl)ethanone 
• 1055924-86-1 N'-(2-cyano-9-methyl-9H-purin-6-yI)-N'-(cyclopentylmethyl)-4-({4-[(1-methyl-4-piperidinyl)methyl]-1-piperazinyl}methyl)benzohydrazide 
• 1055924-96-3 N'-(2-cyano-9-methyl-9H-purin-6-yI)-N'-cyclopentyl-4-({4-[(1-methyl-4-piperidinyl)methyl]-1-piperazinyl}methyl)benzohydrazide 
• 1055925-08-0 N'-(2-cyano-9-methyl-9H-purin-6-yI)-N'-cyclohexyl-4-({4-[(1-methyl-4-piperidinyl)methyl]-1-piperazinyl}methyl)-benzohydrazide 

Relevant academic research and scientific papers

6-PHENYL-2-[((PIPERIDIN-4-YLMETHYL)-PIPERAZIN-1YL) OR PIPERAZIN 1-YLMETHYL)-PIPERIDIN-1-YL)]-IMIDAZO[2,1-B][1,3,4]THIADIAZOLE DERIVATIVES AND THEIR USE

The present invention is directed to novel heterocyclic compounds, their synthesis and pharmaceutical compositions comprising them for the treatment of disorders, in particular, cancer.

HETEROCYCLIC AMIDE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS

Methods and compounds effective in ameliorating conditions characterized by unwanted calcium channel activity, particularly unwanted N-type or T-type calcium channel activity are disclosed. Specifically, a series of heterocyclic amides are disclosed of the general formula (I) where Z is N or CHNR2 and X is NR2, O, S, S=O or SO2. Among other definitions for R, R1, W and Y, the compounds of formula (1) are further characterized by at least one of W or Y being CR3Ar2 where Ar is an aromatic or heteroaromatic ring (for example, where W or Y is a benzhydryl moiety).