496812-79-4Relevant academic research and scientific papers
Synthesis and biological evaluation of (R)- and (S)-2-(phosphonomethyl)pentanedioic acids as inhibitors of glutamate carboxypeptidase II
Vitharana, Dilrukshi,France, Jessica E.,Scarpetti, David,Bonneville, George W.,Majer, Pavel,Tsukamoto, Takashi
, p. 1609 - 1614 (2002)
Both enantiomers of 2-(phosphonomethyl)pentanedioic acid (2-PMPA), a potent and selective inhibitor of glutamate carboxypeptidase II (GCP II), were successfully prepared through the resolution of racemic 2-(hydroxyphosphinoylmethyl)pentanedioic acid diben
