496856-45-2

Usage

Uses

Used in Pharmaceutical Industry:
(3-chloro-4-cyanophenyl)acetic acid methyl ester is used as an intermediate in the synthesis of various pharmaceuticals for its reactivity and versatility in chemical reactions.
Used in Agrochemical Industry:
(3-chloro-4-cyanophenyl)acetic acid methyl ester is used as an intermediate in the synthesis of agrochemicals for its reactivity and versatility in chemical reactions.
Used in Organic Synthesis:
(3-chloro-4-cyanophenyl)acetic acid methyl ester is used as a building block in organic synthesis for its reactivity and versatility in chemical reactions.
Used in Scientific Research:
(3-chloro-4-cyanophenyl)acetic acid methyl ester is used as a research chemical for various scientific studies and applications due to its reactivity and versatility in chemical reactions.

Upstream product

• 496856-44-1 methyl 2-(3-chloro-4-(triuoromethylsulfonyloxy)phenyl)acetate 
• 557-21-1 dicyanozinc 
• 557-21-1 zinc(II) cyanide 
• 57017-95-5 methyl 3-chloro-4-hydroxyphenylacetate 
• 33697-81-3 (3-chloro-4-hydroxy-phenyl)-acetic acid 

Downstream Products

• 927179-96-2 (3-chloro-4-{N-[4-(2,4-dichlorophenoxy)butyl]carbamimidoyl}phenyl)acetic acid methyl ester 
• 870194-52-8 (3-chloro-4-formylphenyl)acetic acid methyl ester 
• 34841-49-1 3-chloro-4-formylbenzeneacetic acid 
• 1428764-92-4 2-(3-chloro-4-(methylsulfonamidomethyl)phenyl)-N-((2-m-tolyl-6-(trifluoromethyl)pyridin-3-yl)methyl)propanamide 
• 1428765-34-7 tert-butyl 2-chloro-4-(1-oxo-1-((2-m-tolyl-6-(trifluoromethyl)pyridin-3-yl)methylamino)propan-2-yl)benzylcarbamate 
• 1428765-36-9 2-(4-(aminomethyl)-3-chlorophenyl)-N-((2-m-tolyl-6-(trifluoromethyl)pyridin-3-yl)methyl)propanamide 
• 870195-37-2 5-(2-chloro-4-methoxycarbonylmethyl-phenyl)-3-phenyl-isoxazole-4-carboxylic acid 
• 870195-38-3 C₁₉H₁₃Cl₂NO₄ 
• 870195-35-0 3-(2-chloro-4-methoxycarbonylmethylphenyl)-3-oxopropionic acid tert-butyl ester 
• 919287-41-5 (3-chloro-4-{5-[4-(2,4-dichloro-phenoxy)-butyryl]-4-phenyl-isoxazol-3-yl}-phenyl)-acetic acid methyl ester 
• 919284-97-2 (3-chloro-4-{4-[2-(2,4-dichloro-phenoxy)-ethyl-carbamoyl]-5-phenyl-isoxazol-3-yl}-phenyl)-acetic acid methyl ester 
• 870194-57-3 (3-chloro-4-{5-methyl-4-[2-(2-nitro-4-trifluoromethyl-phenoxy)-ethoxymethyl]-isoxazol-3-yl}-phenyl)-acetic acid methyl ester 
• 1047643-60-6 (3-chloro-4-{4-[2-(2,4-dichloro-phenoxy)-ethoxymethyl]-5-phenyl-isoxazol-3-yl}-phenyl)-acetic acid methyl ester 
• 919283-66-2 (4-{4-[2-(2,4-bis-trifluoromethyl-phenoxy)-ethylcarbamoyl]-5-methyl-isoxazol-3-yl}-3-chloro-phenyl)-acetic acid methyl ester 

Relevant academic research and scientific papers

ARYL OR N-HETEROARYL SUBSTITUTED METHANESULFONAMIDE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS

The invention relates to aryl or N-heteroaryl substituted methanesulfonamide derivatives of Formula (I) as vanilloid receptor ligands, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.

Aryl or N-heteroaryl Substituted Methanesulfonamide Derivatives as Vanilloid Receptor Ligands

The invention relates to aryl or N-heteroaryl substituted methanesulfonamide derivatives as vanilloid receptor ligands, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.

Amine Substituted Methanesulfonamide Derivatives as Vanilloid Receptor Ligands

The invention relates to amine substituted methanesulfonamide derivatives as vanilloid receptor ligands, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.

AMINE SUBSTITUTED METHANESULFONAMIDE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS

The invention relates to amine substituted methanesulfonamide derivatives of formula (I) as vanilloid receptor ligands, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.

SUBSTITUTED PYRAZOLYL-BASED CARBOXAMIDE AND UREA DERIVATIVES BEARING A PHENYL MOIETY SUBSTITUTED WITH AN N-CONTAINING GROUP AS VANILLOID RECEPTOR LIGANDS

The invention relates to substituted pyrazolyl-based carboxamide and urea derivatives of formula (R) bearing a phenyl moiety substituted with an N-containing group as vanilloid receptor ligands, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.

3,4,5-Trisubstituted isoxazoles as novel PPARδ agonists: Part 1

We report the identification of a novel series of trisubstituted isoxazoles as PPAR activators from a high-throughput screen. A series of structural optimizations led to improved efficacy and excellent functional receptor selectivity for PPARδ. The isoxazoles represent a series of agonists which display a scaffold that lies outside the typical PPAR agonist motif.

COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS

The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of the Peroxisome Proliferator-Activated Receptor (PPAR) families, particularly the activity of PPAR.

COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS

The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of the Peroxisome Proliferator-Activated Receptor (PPAR) families, particularly the activity of PPAR .