496912-11-9

Upstream product

• 939-26-4 2-bromomethylnaphthyl bromide 
• 496912-10-8 {4-[4-(N-hydroxycarbamimidoyl)phenyl]-4-methyl-3-naphthalen-2-ylmethyl-2,5-dioxoimidazolidin-1-yl}acetic acid methyl ester 
• 207735-10-2 [4-(4-cyanophenyl)-4-methyl-3-naphthalen-2-ylmethyl-2,5-dioxoimidazolidin-1-yl]acetic acid methyl ester 
• 169808-01-9 [(R,S)-4-(4-cyanophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]acetic acid methyl ester 

Relevant academic research and scientific papers

Aromatic β-amino acids as Asp-Phg mimics in LDV derived VLA-4 antagonists

Aromatic β-amino acid esters 2a-h were prepared in racemic and enantiomerically pure form by the Radionow reaction or based on the method described by Davis and used as mimics of the Asp-Phg C-terminus in LDV derived VLA-4 antagonists. As a promising β-am