496921-70-1

Basic information

• Product Name: 4H-Indol-4-one, 1-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-1,5,6,7-tetrahydro-
• CAS NO: 496921-70-1
• Molecular Formula: C21H26ClN3O
• Molecular Weight: 371.91
• Mol File: 496921-70-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4H-Indol-4-one, 1-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-1,5,6,7-tetrahydro-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-Indol-4-one, 1-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-1,5,6,7-tetrahydro-(496921-70-1)
• EPA Substance Registry System: 4H-Indol-4-one, 1-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-1,5,6,7-tetrahydro-(496921-70-1)

Safety Data

• Hazardous Substances Data: 496921-70-1(Hazardous Substances Data)

Upstream product

• 13754-86-4 1,5,6,7-tetrahydro-indol-4-one 
• 52605-52-4 1-(3-chloropropyl)-4-(3-chlorophenyl)piperazine hydrochloride 

Relevant articles and documents

TREATMENT OF ORGANOPHOSPHATE EXPOSURE WITH TETRAHYDROINDOLONE ARYLPIPERAZINE COMPOUNDS

A method of treating exposure to organophosphate agents through the use of compounds comprising tetrahydroindolone and arylpiperazine moieties.

Tetrahydroindolone and purine derivatives linked to arylpiperazines

Pharmaceutical composite compositions comprising tetrahydroindolones linked to arylpiperazines and derivatives thereof are disclosed. Specifically, composite compositions useful in treating anti-psychotic disorders are disclosed. The composite compositions disclosed herein can effectively ameliorate symptoms and treat psychotic disorders without causing a decrease in cognitive function. Generally, the composite compounds consist of two moieties, moiety A and B in which a tetrahydroindolone comprises a moiety A linked through a linker L to a moiety B, where B is an arylpiperazinyl moiety. The composite compound provides anti-psychotic actively by interaction with GABA, seratoninne and dopamine receptors. The composite molecules with the combined activities will provide treat psychiatric and neurological diseases without cognitive impairment.