496921-99-4

Upstream product

• 331679-26-6 2,3-O-(D-1,7,7-trimethylbicyclo[2.2.1]hept-6-ylidene)-D-myo-inositol 
• 496921-95-0 C₁₆H₂₆O₆C₁₆H₁₈Si 
• 496921-98-3 1D-5-O-benzoyl-1-O-(tert-butyldiphenylsilyl)-myo-inositol 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 142534-54-1 1D-1-O-(tert-butyldiphenylsilyl)-myo-inositol 
• 496808-43-6 1D-5-O-benzoyl-1-O-(tert-butyldiphenylsilyl)-2,3,4,6-O-tetrakis(methoxymethylene)-myo-inositol 

Downstream Products

• 496922-02-2 1D-2,3,5,6-O-tetrakis(methoxymethylene)-myo-inositol-5-(dibenzyl phosphate) 
• 942914-39-8 1D-O-(1,2-di-O-butanoyl-sn-glycerol-3-O-(cyanoethyl)phospho)-5-(dimethyl methylenephosphonate)-2,3,4,6-O-tetrakis(methoxymethylene)-myo-inositol 
• 942914-40-1 1D-O-(1,2-di-O-oleoyl-sn-glycerol-3-O-(cyanoethyl)phospho)-5-(dimethyl methylenephosphonate)-2,3,4,6-O-tetrakis(methoxymethylene)-myo-inositol 

Relevant academic research and scientific papers

Stabilized phosphatidylinositol-5-phosphate analogues as ligands for the nuclear protein ING2: Chemistry, biology, and molecular modeling

The interaction of PtdIns(5)P with the tumor suppressor protein ING2 has been implicated in the regulation of chromatin modification. To enhance the stability of PtdIns(5)P for studies of the biological role in vivo, two phosphatase-resistant moieties wer

Comprehensive and uniform synthesis of all naturally occurring phosphorylated phosphatidylinositols

Studies of cellular signal transduction mechanisms involving receptor-mediated generation of inositol phosphates and phosphorylated phosphatidylinositols require easy access to these naturally occurring products. Although numerous synthetic methods have been developed during the past decade, most of these methods suffer from excessive length and lack of generality. In this work we describe the comprehensive and uniform synthesis of all naturally occurring phosphatidylinositols such as phosphatidylinositol, phosphatidylinositol 3-phosphate, 4-phosphate, 5-phosphate, 3,4-bisphosphate, 3,5-bisphosphate, 4,5-bisphosphate, and 3,4,5-trisphosphate, featuring both saturated and unsaturated fatty acid chains.