496941-89-0

Upstream product

• 78571-81-0 (R,R)-3-(phenylmethyl)oxiranemethanol 
• 42238-15-3 (2E)-4-phenylbut-2-en-1-ol 
• 496941-80-1 (2R,3R)-1-methoxymethoxy-2,3-epoxy-4-phenylbutane 

Downstream Products

• 496941-78-7 (2S,3R)-2-benzyl-3-(methoxymethoxymethyl)-1-(4-methylphenylsulfonyl)aziridine 

Relevant academic research and scientific papers

Base-promoted elaboration of aziridines

The base-promoted isomerization of aziridines to allyl amines is still an almost unknown reaction. However, the use of superbasic reagents has shown to be able to promote a regio- and stereoselective conversion of monocyclic and bicyclic sulfonyl aziridin

Base promoted isomerization of aziridinyl ethers: a new access to alpha- and beta-amino acids.

Aziridinyl ethers are selectively and easily converted to either amino vinyl ethers or alkoxy allylamines by treatment with mixed metal bases (superbases).