497-78-9

Usage

Uses

Used in Pharmaceutical Industry:
Rhododendrin is used as a pharmaceutical agent for its anti-inflammatory, antioxidant, and anti-cancer properties. It is being studied for its potential health benefits and its ability to modulate various biological pathways, making it a promising candidate for the development of new therapeutic agents.
Used in Traditional Medicine:
Rhododendrin has been employed in traditional medicine for its medicinal properties, including its anti-inflammatory and antioxidant effects. It is used to treat various ailments, but it is important to use caution and follow recommended dosages to avoid potential toxicity.
Used in Cosmetic Industry:
Rhododendrin can be used as an ingredient in cosmetic products due to its antioxidant properties, which can help protect the skin from oxidative stress and promote skin health. However, it is essential to ensure that the product is formulated safely and does not contain excessive amounts of rhododendrin to prevent adverse effects.

InChI:InChI=1/C16H24O7/c1-9(2-3-10-4-6-11(18)7-5-10)22-16-15(21)14(20)13(19)12(8-17)23-16/h4-7,9,12-21H,2-3,8H2,1H3/t9-,12-,13-,14+,15-,16-/m1/s1

Upstream product

• 152339-90-7 rhododendrin pentapivalate 
• 152339-89-4 epi-rhododendrin pentapivalate 
• 152339-87-2 (S)-4-(p-pivaloyloxyphenyl)butan-2-ol 
• 152339-86-1 (S)-4-(4′-methoxyphenyl)-2-butanol 
• 59092-94-3 (+)-rhododendrol 
• 81058-26-6 1,2,3,4,6-penta-O-trimethylacetyl-β-D-glucopyranose 
• 81058-27-7 2,3,4,6-tetra-O-pivaloyl-α-D-glucopyranosyl bromide 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 152339-92-9 (R)-4-(p-pivaloyloxyphenyl)butan-2-ol 
• 39516-05-7 (R)-4-(4′-methoxyphenyl)-2-butanol 
• 152339-88-3 (R)-4-(p-methoxyphenyl)butan-2-ol 3,5-dinitrobenzoate 
• 59092-94-3 (R)-rhododendrol 

Downstream Products

• 59092-94-3 (R)-rhododendrol 
• 59092-94-3 (+)-rhododendrol 
• 92620-71-8 rhododendrin pentaacetate 

Relevant academic research and scientific papers

Chemical synthesis, redox transformation, and identification of sonnerphenolic C, an antioxidant in Acer nikoense

Sonnerphenolic C (3), which was predicted in a redox product of epirhododendrin (1) isolated from Acer nikoense, was synthesized for the first time via the epimeric separation of benzylidene acetal intermediates as a key step. From a similar synthetic route, 1 was obtained concisely. As a result of their antioxidative evaluation, only 3 revealed potent activity. The redox transformation of 1 into 3 was achieved in the presence of tyrosinase and vitamin C. Moreover, 3 was identified in the decoction of A. nikoense by HPLC analysis with the effective use of synthesized 3. Thus, a novel naturally occurring antioxidant 3 was developed through the sequential flow including redox prediction, chemical synthesis, evaluation of the activity, and identification as the natural product.

Synthesis of rhododendrin and epi-rhododendrin,

The first synthesis of rhododendrin 1 and epi-rhododendrin 2 was achieved by starting from ethyl (S)-3-hydroxybutanoate 4, p-bromoanisole and D-glucose.Rhododendrin 1 is known as the hepatoprotective constituent of Taxus baccata L. Keywords: betuligenol / betuloside / epi-rhododendrin / rhododendrin / rhododendrol