497068-73-2 Usage
Uses
Used in Pharmaceutical Industry:
TERT-BUTYL 5-HYDROXY-3,4-DIHYDROQUINOLINE-1(2H)-CARBOXYLATE is used as a pharmaceutical compound for its potential therapeutic properties, including its antioxidant and lipid peroxidation inhibitory effects. Its stability and solubility, attributed to the tert-butyl group, make it suitable for drug formulation.
Used in Neurodegenerative Disorder Treatment:
In the field of neurodegenerative disorders, TERT-BUTYL 5-HYDROXY-3,4-DIHYDROQUINOLINE-1(2H)-CARBOXYLATE may be utilized as a potential therapeutic agent due to its antioxidant properties, which could help in the treatment and management of such conditions.
Used in Cardiovascular Disease Treatment:
TERT-BUTYL 5-HYDROXY-3,4-DIHYDROQUINOLINE-1(2H)-CARBOXYLATE may also have applications in the development of drugs for the treatment of cardiovascular diseases, given its potential to inhibit lipid peroxidation, which can contribute to the prevention or treatment of such conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 497068-73-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,9,7,0,6 and 8 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 497068-73:
(8*4)+(7*9)+(6*7)+(5*0)+(4*6)+(3*8)+(2*7)+(1*3)=202
202 % 10 = 2
So 497068-73-2 is a valid CAS Registry Number.
497068-73-2Relevant academic research and scientific papers
Synthesis and SAR of novel histamine H3 receptor antagonists
Jesudason, Cynthia D.,Beavers, Lisa S.,Cramer, Jeffrey W.,Dill, Joelle,Finley, Don R.,Lindsley, Craig W.,Stevens, F. Craig,Gadski, Robert A.,Oldham, Samuel W.,Pickard, R. Todd,Siedem, Christopher S.,Sindelar, Dana K.,Singh, Ajay,Watson, Brian M.,Hipskind, Philip A.
, p. 3415 - 3418 (2007/10/03)
The synthesis and biological evaluation of novel tetrahydroisoquinoline, tetrahydroquinoline, and tetrahydroazepine antagonists of the human and rat H3 receptors are described. The substitution around these rings as well as the nature of the substituent on nitrogen is explored. Several compounds with high affinity and selectivity for the human and rat H3 receptors are reported.
COMPOUNDS AND METHODS
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Page/Page column 34, (2008/06/13)
Disclosed are compounds and pharmaceutically acceptable salts thereof, useful as LXR agonists.
HISTAMINE H3 RECEPTOR ANTAGONISTS, PREPARATON AND THERAPEUTIC USES
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Page 21, (2010/02/06)
The present invention discloses novel compounds of Formula ( I ) or pharmaceutically acceptable salts thereof which have histamine-H3 receptor antagonist activity as well as methods for preparing such compounds. In another embodiment, the invention disclo
