497108-30-2Relevant academic research and scientific papers
New method for the synthesis of functionalized 1,3-bis-exocyclic dienes via a palladium-catalyzed reaction. Scope and synthetic applications
Lomberget, Thierry,Bouyssi, Didier,Balme, Genevieve
, p. 311 - 329 (2007/10/03)
The palladium-catalyzed tandem cyclization-coupling reaction of conjugated enynes having a stabilizing carbon nucleophile with aryl iodides and vinyl halides or triflates produced stereo-defined, functionalized five- and six-membered 1,3-bis-exocyclic dienes in moderate to good yields. These stereodefined dienes proved to be versatile substrates for the preparation of various polycyclic products through subsequent Diels-Alder, intramolecular Friedel-Crafts or thermal electrocyclization reactions.
Lewis acid-induced intramolecular Friedel-Crafts cyclization of 1,3-bis-exocyclic dienes. A new route to 4a-methyltetrahydrofluorenes
Lomberget, Thierry,Bentz, Emilie,Bouyssi, Didier,Balme, Genevieve
, p. 2055 - 2057 (2007/10/03)
(Matrix presented) An efficient new method for constructing the 4a-methyltetrahydrofluorene skeleton was achieved via Friedel-Crafts intramolecular cyclization of 1,3-bis-exocyclic dienes. This strategy offers a simple and promising method for accessing c
A new route to 1,3-bis-exocyclic dienes using a palladium-mediated cyclization/coupling reaction of conjugated enynes with organic halides and triflates
Lomberget, Thierry,Bouyssi, Didier,Balme, Geneviève
, p. 1439 - 1442 (2007/10/03)
The palladium catalyzed tandem cyclization/coupling reaction of conjugated enynes having a stabilizing carbon nucleophile with unsaturated halides or triflate afforded stereodefined functionalized 1,3-bis-exocyclic dienes. Moderate yields were obtained wi
