497149-52-7

Basic information

• Product Name: Urea, N-[2-chloro-5-(trifluoromethyl)phenyl]-N'-(7-hydroxy-1-naphthalenyl)-
• CAS NO: 497149-52-7
• Molecular Formula: C18H12ClF3N2O2
• Mol File: 497149-52-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Urea, N-[2-chloro-5-(trifluoromethyl)phenyl]-N'-(7-hydroxy-1-naphthalenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Urea, N-[2-chloro-5-(trifluoromethyl)phenyl]-N'-(7-hydroxy-1-naphthalenyl)-(497149-52-7)
• EPA Substance Registry System: Urea, N-[2-chloro-5-(trifluoromethyl)phenyl]-N'-(7-hydroxy-1-naphthalenyl)-(497149-52-7)

Safety Data

• Hazardous Substances Data: 497149-52-7(Hazardous Substances Data)

Upstream product

• 50528-86-4 2-chloro-5-(trifluoromethyl)phenyl isocyanate 
• 118-46-7 8-amino-2-naphthol 

Relevant articles and documents

Naphthol derivatives as TRPV1 inhibitors for the treatment of urinary incontinence

We have identified naphthol derivatives as inhibitors of the vanilloid receptor TRPV1 by high throughput screening. The initial lead showed high clearance in rats and has been optimized by enhancing the acidity of the phenol group. Compound 6b has reduced