497161-76-9

Basic information

• Product Name: 2H-Pyran,2-ethoxy-3,6-dihydro-6-phenyl-,(2S,6S)-(9CI)
• Synonyms: 2H-Pyran,2-ethoxy-3,6-dihydro-6-phenyl-,(2S,6S)-(9CI)
• CAS NO: 497161-76-9
• Molecular Formula: C13H16O2
• Molecular Weight: 204.26
• Product Categories: ETHOXY
• Mol File: 497161-76-9.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2H-Pyran,2-ethoxy-3,6-dihydro-6-phenyl-,(2S,6S)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Pyran,2-ethoxy-3,6-dihydro-6-phenyl-,(2S,6S)-(9CI)(497161-76-9)
• EPA Substance Registry System: 2H-Pyran,2-ethoxy-3,6-dihydro-6-phenyl-,(2S,6S)-(9CI)(497161-76-9)

Safety Data

• Hazardous Substances Data: 497161-76-9(Hazardous Substances Data)

Upstream product

• 24338-69-0 β-(benzoyloxy)acrolein 
• 28557-00-8 phenylzinc chloride 
• 103-75-3 2-ethoxy-2,3-dihydro-4H-pyran 
• 116417-46-0 cis-2-acetoxy-6-ethoxy-5,6-dihydro-2H-pyran 
• 116417-46-0 trans-2-acetoxy-6-ethoxy-5,6-dihydro-2H-pyran 

Relevant articles and documents

Highly enantioselective inverse-electron-demand hetero-Diels-Alder reactions of α,β-unsaturated aldehydes

Straightforward access to useful synthetic intermediates is provided by this new method. Simple, α,β-unsaturated aldehydes are excellent substrates in the hetero-Diels-Alder reaction with inverse electron demand, catalyzed by CrIII-Schiff base complexes (see scheme; R1, R2 = alkyl or aryl) in the presence of 4-A molecular sieves and no solvent. The resulting dihydropyrans are obtained in high enantio- (89-98 % ee) and diastereoselectivity (> 95 % de) and yield (40-95 %).