497163-41-4

Basic information

• Product Name: 8-(2-Aminophenyl)-1,3,5,7-tetrahydro-8H-difuro[3,4-b;3',4'-e]pyran-1,7-dion
• Synonyms: 8-(2-Aminophenyl)-1,3,5,7-tetrahydro-8H-difuro[3,4-b;3',4'-e]pyran-1,7-dion
• CAS NO: 497163-41-4
• Molecular Weight: 285.256
• Mol File: 497163-41-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 8-(2-Aminophenyl)-1,3,5,7-tetrahydro-8H-difuro[3,4-b;3',4'-e]pyran-1,7-dion(CAS DataBase Reference)
• NIST Chemistry Reference: 8-(2-Aminophenyl)-1,3,5,7-tetrahydro-8H-difuro[3,4-b;3',4'-e]pyran-1,7-dion(497163-41-4)
• EPA Substance Registry System: 8-(2-Aminophenyl)-1,3,5,7-tetrahydro-8H-difuro[3,4-b;3',4'-e]pyran-1,7-dion(497163-41-4)

Safety Data

• Hazardous Substances Data: 497163-41-4(Hazardous Substances Data)

Upstream product

• 497163-37-8 3,3'-(2-Nitrobenzyliden)bistetronsaeure 
• 552-89-6 2-nitro-benzaldehyde 
• 497163-39-0 8-(2-Nitrophenyl)-1,3,5,7-tetrahydro-8H-difuro[3,4-b;3',4'-e]pyran-1,7-dion 

Downstream Products

• 4945-38-4 2-hydroxymethylquinoline-3-carboxylic acid lactone 

Relevant articles and documents

Bis(lactone)-annulated 4H-pyranes and 1,4-dihydropyridines from 3,3′-(nitrobenzylidene)-bistetronic acids

The bistetronic derivatives 4, obtained by base catalyzed reaction of the aldehydes 3 with surplus tetronic acid (2), cyclize in polyphosphoric acid (PPA) to yield the 4H-pyranes 5. The amino derivative 6 formed by reduction of the nitro group of 5a easily splits to give the furoquinoline 7 and 2. By heating the ammonium bistetronate 8 ring closure occurs leading to the bisannulated 1,4-dihydropyridine (DHP) 9. The DHP 9 is dehydrogenated to the corresponding pyridine 10. The half wave potentials of the 4H-pyranes 5 and 6 as well as the 1,4-DHP 9 are determined by differential pulse voltammetry.