497172-36-8

Basic information

• Product Name: 2,6-bis[(4R,5S)-4,5-dihydro-4,5-diphenyl-2-oxazolyl]-Pyridine
• Synonyms: 2,6-bis[(4R,5S)-4,5-dihydro-4,5-diphenyl-2-oxazolyl]-Pyridine;2,6-bis((4S,5R)-4,5-diphenyl-4,5-dihydrooxazol-2-yl)pyridine
• CAS NO: 497172-36-8
• Molecular Formula: C35H27N3O2
• Molecular Weight: 521.60778
• Mol File: 497172-36-8.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 711.7±60.0 °C(Predicted)
• Appearance: /
• Density: 1.23±0.1 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 2.55±0.70(Predicted)
• CAS DataBase Reference: 2,6-bis[(4R,5S)-4,5-dihydro-4,5-diphenyl-2-oxazolyl]-Pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-bis[(4R,5S)-4,5-dihydro-4,5-diphenyl-2-oxazolyl]-Pyridine(497172-36-8)
• EPA Substance Registry System: 2,6-bis[(4R,5S)-4,5-dihydro-4,5-diphenyl-2-oxazolyl]-Pyridine(497172-36-8)

Safety Data

• Hazardous Substances Data: 497172-36-8(Hazardous Substances Data)

Usage

General Description

2,6-bis[(4R,5S)-4,5-dihydro-4,5-diphenyl-2-oxazolyl]-Pyridine is a chemical compound with a complex and specific structure. It consists of a pyridine ring with two attached 4,5-dihydro-4,5-diphenyl-2-oxazolyl groups, each with a stereochemistry of (4R,5S). 2,6-bis[(4R,5S)-4,5-dihydro-4,5-diphenyl-2-oxazolyl]-Pyridine is often used in the field of pharmaceuticals and material science for its potential as a fluorescent labeling agent and as a chiral auxiliary in asymmetric synthesis. Its unique structure and properties make it a valuable and versatile tool in various chemical and biological applications.

Upstream product

• 23190-16-1 (1R,2S)-2-Amino-1,2-diphenylethanol 
• 55309-58-5 pyridine-2,6-dicarboximidic acid dimethyl ester 
• 2893-33-6 pyridine-2,6-dinitrile 
• 3739-94-4 2,6-Pyridinedicarbonyl dichloride 
• 530-36-9 (1S,2S)-2-amino-1,2-diphenylethanol 
• 23364-44-5 (1S,2R)-2-Amino-1,2-diphenylethanol 
• 530-36-9 2-amino-1,2-diphenylethanol 
• 410092-96-5 2,6-bis[(1R,2S)-N,N'-2-hydroxy-1,2-diphenylethyl]pyridinedicarboxamide 
• 410092-97-6 2,6-bis[(1R,2S)-N,N'-2-chloro-1,2-diphenylethyl]pyridinedicarboxamide 
• 499-83-2 Pyridine-2,6-dicarboxylic acid 

Relevant articles and documents

Enantioselective Copper Catalyzed Alkyne-Azide Cycloaddition by Dynamic Kinetic Resolution

The copper(I) catalyzed alkyne-azide cycloaddition (CuAAC), a click reaction, is one of the most powerful catalytic reactions developed during the last two decades. Conducting CuAAC enantioselectively would add a third dimension to this reaction and would

Rapid Asymmetric Synthesis of Disubstituted Allenes by Coupling of Flow-Generated Diazo Compounds and Propargylated Amines

We report herein the asymmetric coupling of flow-generated unstabilized diazo compounds and propargylated amine derivatives, using a new pyridinebis(imidazoline) ligand, a copper catalyst and base. The reaction proceeds rapidly, generating chiral allenes in 10–20 minutes with high enantioselectivity (89–98 % de/ee), moderate yields and a wide functional group tolerance.

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