497258-64-7

Upstream product

• 39098-97-0 2-thienylacetic acid chloride 
• 497258-62-5 (+)-pinanediol (1R)-1-(N-bis-trimethylsilylamino)-1-[3-(4,4-dimethyl-4,5-dihydro-oxazol-2-yl)phenyl]methylboronate 
• 497258-61-4 (+)-pinanediol (1S)-1-chloro-1-[3-(4,4-dimethyl-4,5-dihydro-oxazol-2-yl)phenyl]methylboronate 
• 497258-60-3 (+)-pinanediol 3-(4,4-dimethyl-4,5-dihydro-oxazol-2-yl)phenylboronate 
• 51849-84-4 2-(3-bromophenyl)-4,4-dimethyl-2-oxazoline 

Relevant academic research and scientific papers

Nanomolar inhibitors of AmpC β-lactamase

β-lactamases are the most widespread resistance mechanism to β-lactam antibiotics, such as the penicillins and the cephalosporins. In an effort to combat these enzymes, a combination of stereoselective organic synthesis, enzymology, microbiology, and X-ra