497262-00-7

Basic information

• Product Name: [(1R,2R,3S)-2-(bromomethyl)-3-(hydroxymethyl)-2,3-dimethylcyclopentyl]methyl-4-methylbenzene sulfonate
• Synonyms: [(1R,2R,3S)-2-(bromomethyl)-3-(hydroxymethyl)-2,3-dimethylcyclopentyl]methyl-4-methylbenzene sulfonate
• CAS NO: 497262-00-7
• Molecular Weight: 405.353
• Mol File: 497262-00-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: [(1R,2R,3S)-2-(bromomethyl)-3-(hydroxymethyl)-2,3-dimethylcyclopentyl]methyl-4-methylbenzene sulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: [(1R,2R,3S)-2-(bromomethyl)-3-(hydroxymethyl)-2,3-dimethylcyclopentyl]methyl-4-methylbenzene sulfonate(497262-00-7)
• EPA Substance Registry System: [(1R,2R,3S)-2-(bromomethyl)-3-(hydroxymethyl)-2,3-dimethylcyclopentyl]methyl-4-methylbenzene sulfonate(497262-00-7)

Safety Data

• Hazardous Substances Data: 497262-00-7(Hazardous Substances Data)

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 497261-99-1 (1R,2R,3S)-(2-bromomethyl-3-hydroxymethyl-2,3-dimethylcyclopentyl)methanol 
• 497261-97-9 (1R,8R)-8-(bromomethyl)-1,8-dimethyl-3-oxabicyclo[3.2.1]octane-2,4-dione 
• 497261-98-0 (1R,5R,8R)-8-(bromomethyl)-1,8-dimethyl-3-oxabicyclo[3.2.1]octane-2-one 
• 10293-09-1 (1R,4R,7R)-9-bromocamphor 
• 497261-96-8 (1R,7R)-7-(bromomethyl)-1,7-dimethylbicyclo[2.2.1]heptane-2,3-dione 

Downstream Products

• 1027594-31-5 2-{(1R,2R,3S)-2,3-Bis-[(diphenylphosphanyl)-methyl]-1,2-dimethyl-cyclopentylmethoxy}-tetrahydro-pyran 
• 497262-02-9 [(1R,2R,3S)-21,2-dimethyl-2,3-bis(diphenylphosphine-methyl)cyclopentyl]methanol 
• 497262-01-8 [(1R,2R,3S)-2-(bromomethyl)-2,3-dimethyl-3-[(tetrahydro-2H-pyran-2-yloxy)methyl]cyclopentyl]methyl-4-methylbenzenesulfonate 

Relevant articles and documents

A new hydroxydiphosphine as a ligand for Rh(I)-catalyzed enantioselective hydrogenation

A new diphosphine ligand bearing a hydroxy group in the backbone was synthesized starting from 9-bromocamphor. The rhodium(I) complex based on this ligand was tested in the hydrogenation of α- and β-amino acid precursors. The activity and selectivity of the catalyst were found to be strongly dependent upon the nature of the substrate. Thus, β-acetylamino carboxylates were obtained with up to 97% ee.