49739-43-7

Basic information

• Product Name: 4-methyl-3-(phenylsulfonyl)furoxan
• Synonyms: 4-methyl-3-(phenylsulfonyl)furoxan
• CAS NO: 49739-43-7
• Molecular Formula: C₉H₈N₂O₄S
• Molecular Weight: 240.24
• Mol File: 49739-43-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 453°C at 760 mmHg
• Flash Point: 227.8°C
• Appearance: /
• Density: 1.5g/cm³
• Vapor Pressure: 5.75E-08mmHg at 25°C
• Refractive Index: 1.645
• CAS DataBase Reference: 4-methyl-3-(phenylsulfonyl)furoxan(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methyl-3-(phenylsulfonyl)furoxan(49739-43-7)
• EPA Substance Registry System: 4-methyl-3-(phenylsulfonyl)furoxan(49739-43-7)

Safety Data

• Hazardous Substances Data: 49739-43-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H8N2O4S/c1-7-9(11(12)15-10-7)16(13,14)8-5-3-2-4-6-8/h2-6H,1H3

Upstream product

• 49739-36-8 3-methyl-4-(phenylthio)furoxan 
• 108-98-5 thiophenol 
• 142764-04-3 N-Hydroxy-2-[(E)-hydroxyimino]-thiopropionimidic acid phenyl ester 
• 49739-37-9 4-methyl-3-phenylthiofuroxan 
• 49739-41-5 3-methyl-4-phenylsulphonylfuroxan 

Downstream Products

• 1198084-57-9 3-benzylthio-4-methylfuroxan 
• 98384-63-5 5-Benzenesulfonyl-3-oxa-4-aza-tricyclo[5.2.1.0^2,6]dec-4-ene 4-oxide 

Relevant articles and documents

Pharmacochemistry of the furoxan ring: Recent developments

In the present work recent results obtained in the pharmacochemistry of the furoxan system are reported. In particular, after a brief description of the salient points of the furoxan chemistry, the synthesis and the properties of a series of Nifedipine and Prazosin analogues, containing this heterocyclic system, are described. Since we observed that a few furoxan derivatives are able to elicit both a dose-dependent rise in platelet cGMP levels and to promote a dose-dependent inhibition of AA-induced [Ca++] rise, and that many substituted furoxans show potent vasodilating and antiaggregatory activity, the possibility of using the furoxan system as a lead in the design of new vasodilators is also discussed.

Furazan and furoxan sulfones: synthesis and antimicrobial activity

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