4974-86-1

Upstream product

• 67-36-7 4-phenoxy benzaldehyde 
• 925-90-6 ethylmagnesium bromide 
• 555-31-7 aluminum isopropoxide 

Downstream Products

• 103276-21-7 3,4-bis-(4-phenoxy-phenyl)-hexane 
• 60319-66-6 1-phenoxy-4-(prop-1-en-1-yl)benzene 
• 4974-87-2 1-phenoxy-4-(prop-1-en-1-yl)benzene 

Relevant academic research and scientific papers

Mechanistic aspects of aminium salt-catalyzed Diels-Alder reactions: The substrate ionization step

Substituent effects in the aminium salt catalyzed Diels-Alder reactions of 2,3-dimetnyl-1,3-butadiene with a series of meta and para substituted β-methylstyrenes are used to probe detailed mechanistic aspects of these reactions. Kinetic studies were carried out using two different aminium salt catalysts and also electrochemically, using anodic potentials corresponding to the oxidation potentials of the aminium salts. Substituent effects in the equilibrium oxidations of the styrene substrates to the corresponding cation radicals were also studied, via oxidation potential measurements. The results indicate rate determining one electron oxidation of the sytrenes to their cation radicals via an outer sphere electron transfer.

ISOXAZOLINES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE

The present invention provides isoxazoline FAAH inhibitors of the formula (I): or pharmaceutically acceptable forms thereof, wherein each of G, Ra, Rb, Rc, and Rd are as defined herein. The present invention also provides pharmaceutical compositions comprising a compound of formula (I), or a pharmaceutically acceptable form thereof, and a pharmaceutically acceptable excipient. The present invention also provides methods for treating an FAAH-mediated condition comprising administering a therapeutically effective amount of a compound of formula (I), or pharmaceutically acceptable form thereof, to a subject in need thereof.