Z-Gly-ONB, or Z-Glycine Ortho-Nitrobenzyl Ester, is a chemical compound commonly used in peptide synthesis and biochemistry. It is a protected amino acid derivative, where the carboxylic acid group of glycine is esterified with an ortho-nitrobenzyl (ONB) group. This protection is crucial for preventing unwanted side reactions during peptide synthesis. The Z group, or benzyloxycarbonyl group, is a temporary protecting group that shields the amino group of glycine, allowing for controlled coupling reactions in solid-phase peptide synthesis. Z-Gly-ONB is particularly useful for the synthesis of peptides that require the introduction of a free carboxyl group at a specific position within the peptide sequence. Upon completion of the synthesis, the ONB protecting group can be removed under mild conditions, such as exposure to light, to reveal the free carboxyl group. Z-Gly-ONB is an essential tool in the field of peptide chemistry, enabling the creation of complex peptide structures with precise functional groups.
49761-46-8
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Basic information
- Product Name: Z-Gly-ONB
- Synonyms: Z-Gly-ONB
- CAS NO:49761-46-8
- Molecular Formula:
- Molecular Weight: 370.362
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: N/A
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: Z-Gly-ONB(CAS DataBase Reference)
- NIST Chemistry Reference: Z-Gly-ONB(49761-46-8)
- EPA Substance Registry System: Z-Gly-ONB(49761-46-8)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 49761-46-8(Hazardous Substances Data)
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Check Digit Verification of cas no
The CAS Registry Mumber 49761-46-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,9,7,6 and 1 respectively; the second part has 2 digits, 4 and 6 respectively.Calculate Digit Verification of CAS Registry Number 49761-46:
(7*4)+(6*9)+(5*7)+(4*6)+(3*1)+(2*4)+(1*6)=158
158 % 10 = 8
So 49761-46-8 is a valid CAS Registry Number.
49761-46-8Upstream product
49761-46-8Downstream Products
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- 69408-31-7 Z-Gly-γAbu-OBzl
- 74509-18-5 Z-Gly-Phe-Leu-Pro-OBut
- 74086-18-3 {[(S)-2-(N'-Acetyl-hydrazino)-1-benzyl-2-oxo-ethylcarbamoyl]-methyl}-carbamic acid benzyl ester
- 74085-58-8 {[(S)-1-Benzyl-2-oxo-2-(N'-propionyl-hydrazino)-ethylcarbamoyl]-methyl}-carbamic acid benzyl ester
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Z-Gly-ONB
