49764-17-2

Basic information

• Product Name: 1-(4-methoxyphenoxy)tricyclo[3.3.1.1~3,7~]decane
• Synonyms: 1-(4-Methoxyphenoxy)adamantane; tricyclo[3.3.1.1~3,7~]decane, 1-(4-methoxyphenoxy)-
• CAS NO: 49764-17-2
• Molecular Formula: C₁₇H₂₂O₂
• Molecular Weight: 258.3554
• Mol File: 49764-17-2.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 369.7°C at 760 mmHg
• Flash Point: 142.8°C
• Density: 1.134g/cm³
• Vapor Pressure: 2.48E-05mmHg at 25°C
• Refractive Index: 1.573
• CAS DataBase Reference: 1-(4-methoxyphenoxy)tricyclo[3.3.1.1~3,7~]decane(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-methoxyphenoxy)tricyclo[3.3.1.1~3,7~]decane(49764-17-2)
• EPA Substance Registry System: 1-(4-methoxyphenoxy)tricyclo[3.3.1.1~3,7~]decane(49764-17-2)

Safety Data

• Hazardous Substances Data: 49764-17-2(Hazardous Substances Data)

Upstream product

• 768-95-6 1-adamanthanol 
• 696-62-8 para-iodoanisole 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 623-12-1 4-chloromethoxybenzene 
• 768-90-1 1-Adamantyl bromide 
• 150-76-5 4-methoxy-phenol 

Downstream Products

• 55087-18-8 1-(4-Methoxy-2-nitro-phenoxy)-adamantane 
• 54929-15-6 1-(4-Methoxy-3-nitro-phenoxy)-adamantane 

Relevant articles and documents

CgPhen-DalPhos Enables the Nickel-CatalyzedO-Arylation of Tertiary Alcohols with (Hetero)Aryl Electrophiles

While the Ni-catalyzed cross-coupling of primary or secondary aliphatic alcohols and (hetero)aryl electrophiles is known, related cross-couplings involving tertiary aliphatic alcohols, with a broad scope, are challenging. Herein we disclose that a NiIIprecatalyst featuring the ligand CgPhen-DalPhos is unusual in its ability to promote the C-O cross-coupling of tertiary aliphatic alcohols with (hetero)aryl halides (Cl, Br, and I) or phenol derivatives (OMs and OPiv). An exploration of substrate scope and competition experiments help to shed light on the capabilities and reactivity preferences of this catalyst system.