49769-28-0

Upstream product

• 591-50-4 iodobenzene 
• 30964-00-2 hept-6-ynoic acid 
• 49769-24-6 5-(4-phenyl-[1,2,3]selenadiazol-5-yl)-pentanoic acid ethyl ester 
• 93864-39-2 7-phenyl-7-semicarbazono-heptanoic acid 
• 335353-53-2 7-phenyl-hept-6-yn-1-ol 
• 49769-23-5 5-(4-phenyl-[1,2,3]selenadiazol-5-yl)-pentanoic acid 

Downstream Products

• 135191-03-6 N-(2-iodophenyl)-7-phenyl-6-heptynamide 
• 889452-33-9 4-methyl-N-(7-phenyl-hept-6-ynoyl)-benzenesulfonamide 
• 889452-32-8 7-phenyl-hept-6-ynoic acid benzylamide 
• 75649-59-1 (E)-6-styryltetrahydro-2H-pyran-2-one 
• 135190-93-1 9-Methyl-4-phenyl-2,3,9,10a-tetrahydro-1H-9-aza-benzo[f]azulen-10-one 
• 135190-87-3 N-methyl-N-phenyl-2-benzylidenecyclopentanecarboxamide 
• 135190-68-0 N-(2-iodophenyl)-N-methyl-7-phenyl-6-heptynamide 
• 848068-44-0 7-phenylhept-6-ynoyl chloride 
• 1186400-10-1 5-(oxiran-2-yl)pentyl 7-phenylhept-6-ynoate 
• 62808-75-7 7-phenyl-5-oxohept-6-ynoic acid 

Relevant academic research and scientific papers

Copper-Free Sonogashira coupling in water with an amphiphilic resin-supported palladium complex

The palladium-catalyzed coupling reaction of aryl halides with terminal alkynes, the Sonogashira coupling, took place in water under copper-free conditions by use of an amphiphilic polystyrene-poly(ethylene glycol) (PS-PEG) resin-supported palladium-phosphine complex to give the corresponding aryl-substituted alkynes in high yields. The PS-PEG resin-supported palladium catalyst was recovered by simple filtration and reused four times without any loss of catalytic activity.

EFFICIENT SYNTHESIS OF AMINES AND AMIDES FROM ALCOHOLS AND ALDEHYDES BY USING CASCADE CATALYSIS

The present invention relates generally to an eco-friendly methodology for the conversion of alcohols and aldehydes to amines and amides using an integrated enzyme cascade system with metal-and organocatalysis. More specifically, the present invention relates to synthesis of capsaicinoids starting from vanillin alcohol and using a combination of an enzyme cascade system and catalysts. Furthermore, the method also relates to synthesis of capsaicinoids derivatives starting from vanillin alcohol derivatives and using a combination of an enzyme cascade system and catalysts.

Lactam synthesis via the intramolecular hydroamidation of alkynes catalyzed by palladium complexes

The palladium complexes catalyzed intramolecular hydroamidation reaction of amidoalkynes gives the corresponding lactams in good to high yields. For example, in the presence of 10 mol % of Pd(PPh3)4 and 20 mol % of PhCOOH, the reacti

CAPSAICIN DERIVATES AND THE PRODUCTION AND USE THEREOF

The invention relates to new compounds, namely capsaicin derivates, a new method for their production, and their use as micro-organism-repellent agents in paints and coatings, in particular for marine installations and ships, but also for land-based struc

The sonogashira reaction in water via an amphiphilic resin-supported palladium-phosphine complex under copper-free conditions

The Sonogashira reaction of aryl halides with terminal alkynes was catalyzed by an amphiphilic polystyrene-poly(ethylene glycol) (PS-PEG) resin-supported palladium-phosphine complex in water to give the corresponding aryl-substituted alkynes in high yields under copper-free conditions. Reaction of o-iodophenol with terminal alkynes under Sonogashira conditions gave benzofuran derivatives in one step.