49771-77-9Relevant academic research and scientific papers
A New Route to Chiral Bis-tertiary Phosphine Ligands: Synthesis, Resolution, and Crystal Structure of trans-Bis-1,2-(diphenylphosphino)cyclopentane and the Nickel Adduct NiBr2
Allen, David L.,Gibson, Vernon C.,Green, Malcolm L. H.,Skinner, James F.,Bashkin, Jim,Grebenik, Peter D.
, p. 895 - 896 (2007/10/02)
Heating of white phosphorus, phosphorus trichloride, and cyclopentene at 220 deg C gives trans-1,2-bis(dichlorophosphino)cyclopentane (1), which with phenylmagnesium bromide gives trans-1,2-bis(diphenylphosphino)cyclopentane (dpcp) (2); compound (2) forms the adduct Ni(dpcp)Br2*CH2Cl2, which readily crystallises as a conglomerate and the pure enantiomers may be separated by hand allowing resolution of (2), and catalytic hydrogenation of methyl(N-benzoyl)dehydrophenylalanine using resolved (2) and a rhodium catalyst gave a hydrogenated product of 100percent optical purity.
