49772-15-8Relevant academic research and scientific papers
Efficient one-step synthesis of 3-aryl-2-pyridones from 6-aryl-1,2,4-triazin-5-ones
Savchuk, Maria I.,Shtaitz, Yaroslav K.,Kopchuk, Dmitry S.,Zyryanov, Grigory V.,Eltsov, Oleg S.,Pospelova, Tatiana А.,Rusinov, Vladimir L.,Chupakhin, Oleg N.
, p. 985 - 988 (2019)
[Figure not available: see fulltext.] An efficient method for the synthesis of substituted 2-pyridones based on the aza-Diels–Alder reaction of 1,2,4-triazin-5-ones and dienophiles, 2,5-norbornadiene and 4-(cyclopent-1-en-1-yl)morpholine, is proposed.
Discovery of a new molecular probe ML228: An activator of the hypoxia inducible factor (HIF) pathway
Theriault, Jimmy R.,Felts, Andrew S.,Bates, Brittney S.,Perez, Jose R.,Palmer, Michelle,Gilbert, Shawn R.,Dawson, Eric S.,Engers, Julie L.,Lindsley, Craig W.,Emmitte, Kyle A.
experimental part, p. 76 - 81 (2012/02/16)
Hypoxia and ischemia are linked to several serious public health problems that affect most major organ systems. Specific examples include diseases of the cardiovascular, pulmonary, renal, neurologic, and musculoskeletal systems. The most significant pathw
