497845-56-4Relevant academic research and scientific papers
A convenient synthetic access to δ-amino-γ,γ-difluoro-β-ketoesters
Wang, Yanli,Zhu, Shizheng
, p. 1813 - 1818 (2002)
The zinc-cuprous chloride promoted Reformatsky-imine addition reaction of 4-bromo-4,4-difluoroacetoacetate with aldimines derived from aromatic aldehydes and with ketimines derived from aryl alkyl ketone provided an efficient and practical access to δ-amino-γ,γ-difluoro-β-ketoesters. The scope and limitation of this procedure are also discussed.
Convenient synthesis of polyfunctionalized β-fluoropyrroles from rhodium(II)-catalyzed intramolecular N-H insertion reactions
Wang, Yanli,Zhu, Shizheng
, p. 745 - 748 (2007/10/03)
(Matrix presented) Polyfunctionalized β-fluoropyrrole can be readily prepared from rhodium(II) acetate-catalyzed intramolecular N-H insertion reaction of δ-amino-γ,γ-difluoro-α-diazo-β -ketoesters. A cyanomethylene group can be introduced at C-3 of the py
