497847-40-2

Upstream product

• 1066-54-2 trimethylsilylacetylene 
• 291758-13-9 (R)-1,4-anhydro-2-O-(2,4-dimethoxybenzoyl)-3,5-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-4-sulfinyl-D-ribitol 
• 497847-37-7 N⁴-benzoyl-1-[2-O-(tert-butyldimethylsilyl)-4-thio-β-D-ribofuranosyl]cytosine 
• 497847-32-2 N⁴-benzoyl-1-[2-O-(2,4-dimethoxybenzoyl)-3,5-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-4-thio-β-D-ribofuranosyl]cytosine 
• 1054656-82-4 N-{1-[(2R,3R,3aS,9aR)-3-(tert-Butyl-dimethyl-silanyloxy)-5,5,7,7-tetraisopropyl-tetrahydro-4,6,8-trioxa-1-thia-5,7-disila-cyclopentacycloocten-2-yl]-2-oxo-1,2-dihydro-pyrimidin-4-yl}-benzamide 
• 497847-38-8 N⁴-benzoyl-1-[2,5-bis-O-(tert-butyldimethylsilyl)-4-thio-β-D-ribofuranosyl]cytosine 
• 497847-36-6 N⁴-benzoyl-1-[3,5-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-4-thio-β-D-ribofuranosyl]cytosine 
• 497847-39-9 N⁴-benzoyl-1-[2,5-bis-O-(tert-butyldimethylsilyl)-4-thio-β-D-ribofuran-3-ulosyl]cytosine 
• 497847-35-5 1-[3,5-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-4-thio-β-D-ribofuranosyl]cytosine 

Relevant academic research and scientific papers

Synthesis and structural elucidation of 1-(3-C-ethynyl-4-thio-β-D-ribofuranosyl)cytosine (4′-thioECyd)

A practical synthesis of 1,4-anhydro-4-thio-D-ribitol (5) via 1,4-dibromo-1,4-dideoxy-2,3,5-tri-O-benzyl-L-lyxitol (12) is described. This method reduced our previous eleven step procedure starting from D-ribose by three steps. The Pummerer reaction of 1,