Cas 497860-87-4,17-[2-(dimethylamino)ethylamino]-11-oxo-17-demethyoxygeldanamycin

497860-87-4

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Basic information

Product Name: 17-[2-(dimethylamino)ethylamino]-11-oxo-17-demethyoxygeldanamycin
Synonyms: 17-[2-(dimethylamino)ethylamino]-11-oxo-17-demethyoxygeldanamycin
CAS NO:497860-87-4
Molecular Formula:
Molecular Weight: 614.739
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 17-[2-(dimethylamino)ethylamino]-11-oxo-17-demethyoxygeldanamycin(CAS DataBase Reference)
NIST Chemistry Reference: 17-[2-(dimethylamino)ethylamino]-11-oxo-17-demethyoxygeldanamycin(497860-87-4)
EPA Substance Registry System: 17-[2-(dimethylamino)ethylamino]-11-oxo-17-demethyoxygeldanamycin(497860-87-4)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 497860-87-4(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 497860-87-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,9,7,8,6 and 0 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 497860-87:
(8*4)+(7*9)+(6*7)+(5*8)+(4*6)+(3*0)+(2*8)+(1*7)=224
224 % 10 = 4
So 497860-87-4 is a valid CAS Registry Number.

497860-87-4Upstream product

467214-20-6 alvespimycin

497860-87-4Downstream Products

497860-87-4Relevant academic research and scientific papers

Potent cytotoxic C-11 modified geldanamycin analogues

Tian, Zong-Qiang,Wang, Zhan,MacMillan, Karen S.,Zhou, Yiqing,Carreras, Christopher W.,Mueller, Thomas,Myles, David C.,Liu, Yaoquan

, p. 3265 - 3273 (2009)

17-Allylamino-17-demethoxygeldanamycin (17-AAG) inhibits the activity of Hsp90, an important target for treatment of cancers. In an effort to identify analogues of geldanamycin (GDM) with properties superior to those of 17-AAG, we synthesized C-11 modifie

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