497862-94-9Relevant academic research and scientific papers
Sulfonamide derivatives of bridgehead substituted bicyclo[4.2.1]nonanes as γ-secretase inhibitors
Sparey, Tim,Clarke, Earl,Hannam, Joanne,Harrison, Timothy,Madin, Andrew,Shearman, Mark,Sohal, Bindi
, p. 375 - 379 (2008)
Bridgehead substituted derivatives of bicyclo[4.2.1]nonanes were synthesized and shown to be potent inhibitors of γ-secretase. Two related series were synthesized to explore the SARs. More potent compounds were found in the non-benzofused series compared
