497868-49-2

Upstream product

• 104-53-0 3-phenyl-propionaldehyde 
• 216569-16-3 (5R)-5-Phenyl[1,3,4]oxadiazinan-2-one 

Downstream Products

• 497868-54-9 (3R,4S,5S)-1,2-dibenzoyl-5-phenethylpyrazolidine-3,4-dicarboxylic acid dimethyl ester 
• 497868-55-0 (3S,4S,5S)-1,2-dibenzoyl-5-phenethylpyrazolidine-3,4-dicarboxylic acid dimethyl ester 
• 497868-50-5 (4R,6S,7S,8R)-1-oxo-6-phenethyl-4-phenyltetrahydropyrazolo[1,2-c][1,3,4]oxadiazine-7,8-dicarboxylic acid dimethyl ester 

Relevant academic research and scientific papers

Asymmetric synthesis of densely functionalized pyrazolidines and 1,3-diamines

A versatile and straightforward access to polysubstituted 1,3-diamines with good control of relative and absolute configurations is described. The key steps involve a diastereoselective 1,3-dipolar cycloaddition of a chiral non-racemic azomethine imine ylide and a chemoselective electroreduction of densely functionalized pyrazolidines intermediates.