497944-82-8Relevant academic research and scientific papers
Regioselective N-alkylation with alcohols for the preparation of 2-(N-alkylamino)quinazolines and 2-(N-alkylamino)pyrimidines
Li, Feng,Chen, Lin,Kang, Qikai,Cai, Jianguang,Zhu, Guangjun
, p. 624 - 631 (2013/03/28)
In the presence of the [Cp*IrCl2]2/NaOH system, the direct N-alkylation of 2-aminoquinazolines and 2-aminopyrimidines with alcohols afforded the N-exosubstituted 2-(N-alkylamino)quinazolines and 2-(N-alkylamino)pyrimidines with 71-96
